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Key Documents

CBL212

Sigma-Aldrich

Anti-Neurofilament 200 kDa Antibody, clone RT97

clone RT97, Chemicon®, from mouse

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About This Item

Code UNSPSC :
12352203
eCl@ss :
32160702
Nomenclature NACRES :
NA.41

Source biologique

mouse

Niveau de qualité

Forme d'anticorps

purified antibody

Clone

RT97, monoclonal

Espèces réactives

rat, human, pig, avian, chicken, reptile

Réactivité de l'espèce (prédite par homologie)

mammals

Fabricant/nom de marque

Chemicon®

Technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable

Isotype

IgG1

Numéro d'accès NCBI

Numéro d'accès UniProt

Conditions d'expédition

wet ice

Spécificité

The clone RT97 recognizes the 200 kDa neurofilament polypeptide in a number of mammalian and avian species. Tumours specifically recognized include phaeochromocytoma, paraganglioma, ganglioneuroblastoma and other tumours of neuronal origin.

KNOWN SPECIES CROSS REACTIVITY: Recognizes rat, chicken, pig and reptile

Application

Anti-Neurofilament 200 kDa Antibody, clone RT97 detects level of Neurofilament 200 kDa & has been published & validated for use in IH, IH(P).
Research Category
Neuroscience
Research Sub Category
Neurofilament & Neuron Metabolism

Neuronal & Glial Markers
Staining of both frozen and paraffin wax embedded tissue sections

Strong staining of neuronal processes in a variety of tissues

Optimal working dilutions must be determined by the end user.

Forme physique

Format: Purified
The monoclonal is presented in phosphate buffered saline containing 10mM sodium azide and 1mg/ml bovine serum albumin. We recommend that each laboratory determine an optimum working titre for use in its particular application.

Stockage et stabilité

Stable for 1 year at 2-8°C from date of receipt

Autres remarques

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Informations légales

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Code de la classe de stockage

12 - Non Combustible Liquids

Classe de danger pour l'eau (WGK)

WGK 2

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable


Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Consulter la Bibliothèque de documents

Stephen M F Jamieson et al.
Molecular pain, 5, 66-66 (2009-11-20)
Oxaliplatin and related chemotherapeutic drugs cause painful chronic peripheral neuropathies in cancer patients. We investigated changes in neuronal size profiles and neurofilament immunoreactivity in L5 dorsal root ganglion (DRG) tissue of adult female Wistar rats after multiple-dose treatment with oxaliplatin
Signals for the initiation and termination of synthesis of the viral strand of bacteriophage f1.
Dotto, G P, et al.
Cold Spring Harbor Symposia on Quantitative Biology, 47 Pt 2, 717-722 (1983)
Hisashi Hashimoto et al.
Neuro-degenerative diseases, 17(4-5), 181-198 (2017-05-11)
A novel ataxic mouse line was established from the offspring of a male mouse administered cyclophosphamide in a juvenile period. We have attempted to examine the phenotype and histopathological changes of affected mice. Furthermore, linkage analysis and sequencing of the
Adi Nitzan-Luques et al.
Pain, 152(10), 2413-2426 (2011-08-30)
Pain is normally mediated by nociceptive Aδ and C fibers, while Aβ fibers signal touch. However, after nerve injury, Aβ fibers may signal pain. Using a genetic model, we tested the hypothesis that phenotypic switching in neurotransmitters expressed by Aβ
Iris Adam et al.
Current biology : CB, 31(14), 3115-3124 (2021-06-06)
The motor control resolution of any animal behavior is limited to the minimal force step available when activating muscles, which is set by the number and size distribution of motor units (MUs) and muscle-specific force. Birdsong is an excellent model

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