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8.04518

N-Hydroxysuccinimide

≥99.0% (acidimetric), for peptide synthesis

Synonyme(s) :

N-Hydroxysuccinimide, 1-Hydroxy-2,5-pyrrolidinedione

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A propos de cet article

Formule empirique (notation de Hill) :
C4H5NO3
Numéro CAS:
Poids moléculaire :
115.09
UNSPSC Code:
12352115
EC Index Number:
228-001-3
NACRES:
NA.22
MDL number:
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Nom du produit

N-Hydroxysuccinimide, for synthesis

Quality Segment

assay

≥99.0% (acidimetric)

form

crystals

reaction suitability

reaction type: Addition Reactions

pH

5-7 (20 °C, 50 g/L in H2O)

mp

93-100 °C

application(s)

peptide synthesis

SMILES string

N1(C(=O)CCC1=O)O

InChI

1S/C4H5NO3/c6-3-1-2-4(7)5(3)8/h8H,1-2H2

InChI key

NQTADLQHYWFPDB-UHFFFAOYSA-N

Application

  • Direct Cα-heteroarylation of structurally diverse ethers: This study showcases a mild N-hydroxysuccinimide mediated cross-dehydrogenative coupling reaction, expanding the utility of NHS in organic synthesis. (Liu et al., 2017).

Analysis Note

Assay (acidimetric): ≥ 99.0 %
Melting range (lower value): ≥ 95 °C
Melting range (upper value): ≤ 100 °C
Identity (IR): passes test

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Cet article
13067256480774324
description

for synthesis

description

98%

description

purum, ≥97.0% (T)

description

96%

form

crystals

form

solid

form

solid

form

solid

assay

≥99.0% (acidimetric)

assay

98%

assay

≥97.0% (T)

assay

96%

mp

93-100 °C

mp

95-98 °C (lit.)

mp

95-98 °C

mp

136-138 °C

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

100

application(s)

peptide synthesis

application(s)

-

application(s)

peptide synthesis

application(s)

-

pH

5-7 (20 °C, 50 g/L in H2O)

pH

-

pH

-

pH

-


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pictograms

Corrosion

signalword

Danger

hcodes

Hazard Classifications

Eye Dam. 1 - Skin Irrit. 2

Classe de stockage

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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Questions

1–2 of 2 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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