56480

N-Hydroxysuccinimide

≥97.0% (T), for peptide synthesis

• Synonyme(s) : 1-Hydroxy-2,5-pyrrolidinedione, HOSu, NHS
• Formule empirique (notation de Hill) : C₄H₅NO₃
• Numéro CAS: 6066-82-6
• Poids moléculaire : 115.09
• NACRES: NA.22
• PubChem Substance ID: 329758217
• UNSPSC Code: 12352005
• EC Number: 228-001-3
• MDL number: MFCD00005516
• Beilstein/REAXYS Number: 113913

Propriétés

• Nom du produit: N-Hydroxysuccinimide, purum, ≥97.0% (T)
• grade: purum
• Quality Segment: 200
• assay: ≥97.0% (T)
• form: solid
• reaction suitability: reaction type: Addition Reactions
• mp: 95-98 °C
• application(s): peptide synthesis
• functional group: imide
• SMILES string: ON1C(=O)CCC1=O
• InChI: 1S/C4H5NO3/c6-3-1-2-4(7)5(3)8/h8H,1-2H2
• InChI key: NQTADLQHYWFPDB-UHFFFAOYSA-N

Description

Application

N-Hydroxysuccinimide (NHS) can be used in the following applications:

• To synthesize N-succinimidyl 3-(2-pyridyldithio)-propionate, a heterobifunctional reagent useful for protein-protein conjugation and also to incorporate aliphatic thiols into proteins.
• To synthesize NHS esters of long-chain fatty acids.
• NHS can activate the phosphonic acid monolayers immobilized on titanium surface for binding with proteins.

Other Notes

may contain 1-3% succinic acid and/or succinic anhydride

Informations sur la sécurité

• pictograms: GHS05
• signalword: Danger
• hcodes: H315,H318
• pcodes: P264 - P280 - P302 + P352 - P305 + P351 + P338 - P332 + P313 - P362 + P364
• Hazard Classifications: Eye Dam. 1 - Skin Irrit. 2
• Classe de stockage: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)