238470

Cremophor^® EL

• Synonyme(s) : Castor oil polyoxyethylene ether, Ethoxylated castor oil, PEG-35 castor oil, Polyoxyl 35 castor oil, polyoxyl 35 castor oil
• Numéro CAS: 61791-12-6
• Numéro MDL: MFCD00130879
• Code UNSPSC : 12162002
• Nomenclature NACRES : NA.21

Propriétés

• Forme: liquid
• Niveau de qualité: 100
• Fabricant/nom de marque: Calbiochem^®
• Conditions de stockage: OK to freeze; protect from light
• Couleur: clear pale yellow
• CMC: ~0.02%
• Solubilité: ethanol: soluble; water: soluble, clear (at higher temperatures the solution will be come turbid)
• Conditions d'expédition: ambient
• Température de stockage: 2-8°C
• InChI: 1S/C4H7Cl2NO2/c5-1-3(2-6)9-4(7)8/h3H,1-2H2,(H2,7,8)
• Clé InChI: JMNCUXPHXKHBPY-UHFFFAOYSA-N

Description

Description générale

1 Set = 5 X 25 GM

A mixture of polyoxyethylated triglycerides, by reacting castor oil with ethylene oxide in a molar ratio of 1 : 35, that acts as a nonionic surfactant and serves as a formulation vehicle (p.o. and i.v. administration) for poorly-water soluble pharmacological agents.

Hydrophilic-lipophilic balance (HLB) ~ 12 - 14.

Application

• Proteomic responses of carotenoid and retinol administration to Mongolian gerbils.: This research examines the proteomic responses in Mongolian gerbils administered with carotenoids and retinol. Cremophor^® EL is utilized as a solubilizing agent for these compounds, highlighting its role in biochemical studies involving lipid-soluble substances (Bohn et al., 2018).

Conditionnement

Packaged under inert gas

Avertissement

Toxicity: Standard Handling (A)

Autres remarques

Gelderblom, H., et al. 2001. Eur. J. Cancer37, 1590.

Sparreboom, A., et al. 1996. Cancer Res.56, 2112.
Woodcock, D.M., et al. 1990. Cancer Res.50, 4199.

Informations légales

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Cremophor is a registered trademark of BASF SE

Informations sur la sécurité

• Code de la classe de stockage: 10 - Combustible liquids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): 494.6 °F - Not applicable
• Point d'éclair (°C): 257 °C - Not applicable