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Merck
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07-633

Sigma-Aldrich

Anti-HNF3β/FOXA2 Antibody

Upstate®, from rabbit

Synonyme(s) :

Anti-HNF-3-beta, Anti-HNF3B, Anti-TCF3B

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About This Item

Code UNSPSC :
12352203
eCl@ss :
32160702
Nomenclature NACRES :
NA.41

Source biologique

rabbit

Forme d'anticorps

purified immunoglobulin

Type de produit anticorps

primary antibodies

Clone

polyclonal

Espèces réactives

mouse, human, rat

Fabricant/nom de marque

Upstate®

Technique(s)

immunohistochemistry: suitable
western blot: suitable

Isotype

IgG

Numéro d'accès UniProt

Conditions d'expédition

wet ice

Modification post-traductionnelle de la cible

unmodified

Informations sur le gène

human ... FOXA2(3170)
mouse ... Foxa2(15376)
rat ... Foxa2(25099)

Description générale

This gene encodes a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific transcripts such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver. This gene has been linked to sporatic cases of maturity-onset diabetes of the young. Two transcript variants encoding the same protein have been identified for this gene.

Spécificité

Recognizes HNF3β/FOXA2.

Immunogène

GST fusion protein corresponding to residues 7-86 of rat hepatocyte nuclear factor-3 beta / forkhead box A2 (HNF3β/FOXA2)

Application

Detect HNF3β/FOXA2 with Anti-HNF3β/FOXA2 Antibody (Rabbit Polyclonal Antibody), that has been shown to work in IHC & WB.
Research Category
Epigenetics & Nuclear Function
Research Sub Category
Transcription Factors

Qualité

Routinely evaluated by immunoblot with nuclear extracts from MLE 12 cells

Description de la cible

50 kDa

Forme physique

Format: Purified
Protein A Purified rabbit IgG in a solution of 30% glycerol, 0.07M Tris-glycine, pH 7.4, 0.135M NaCl, and 0.035% sodium azide as a preservative.
Protein A purified

Stockage et stabilité

Maintain for 2 years at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Remarque sur l'analyse

Control
MLE 12 nuclear extracts, human liver lysate

Autres remarques

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Informations légales

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Code de la classe de stockage

10 - Combustible liquids

Classe de danger pour l'eau (WGK)

WGK 1


Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Consulter la Bibliothèque de documents

Mesenchymal expression of Tbx4 gene is not altered in Adriamycin mouse model.
Piotr Hajduk,Paula Murphy,Prem Puri
Pediatric Surgery International null
Comparative evaluation of biofilm formation and tolerance to a chemical shock of pathogenic and nonpathogenic Escherichia coli O157:H7 strains.
Marouani-Gadri N, Chassaing D, Carpentier B
Journal of Food Protection null
Circadian regulation of intestinal lipid absorption by apolipoprotein AIV involves forkhead transcription factors A2 and O1 and microsomal triglyceride transfer protein.
Pan, X; Munshi, MK; Iqbal, J; Queiroz, J; Sirwi, AA; Shah, S; Younus, A; Hussain, MM
The Journal of Biological Chemistry null
Forkhead box A2 transcription factor is expressed in all types of neuroendocrine lung tumors
Khoor, Andras, et al.
Human Pathology, 35, 560-564 (2004)
Temporal-spatial distribution of hepatocyte nuclear factor-3beta in developing human lung and other foregut derivatives.
Stahlman, M T, et al.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 46, 955-962 (1998)

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