C-243

C-Peptide solution

100 μg/mL (Protease-free 1x PBS), certified reference material, ampule of 0.5 mL, Cerilliant^®

• Formule empirique (notation de Hill): C₁₂₉H₂₁₁N₃₅O₄₈
• Numéro CAS: 33017-11-7
• Poids moléculaire : 3020.26
• Code UNSPSC : 12352209
• Nomenclature NACRES : NA.24

Propriétés

• Qualité: certified reference material
• Niveau de qualité: 300
• Caractéristiques: Snap-N-Spike^®/Snap-N-Shoot^®
• Conditionnement: ampule of 0.5 mL
• Fabricant/nom de marque: Cerilliant^®
• Concentration: 100 μg/mL (Protease-free 1x PBS)
• Format: single component solution
• Température de stockage: −20°C
• InChI: 1S/C129H211N35O48/c1-58(2)42-77(155-113(195)74(31-39-102(184)185)151-127(209)105(65(15)16)162-114(196)71(25-32-88(131)167)145-95(174)54-141-126(208)104(64(13)14)161-115(197)72(26-33-89(132)168)150-118(200)80(45-61(7)8)156-121(203)83(48-103(186)187)159-112(194)73(30-38-101(182)183)148-107(189)67(18)143-109(191)69(130)24-36-99(178)179)111(193)138-50-93(172)135-49-92(171)136-55-98(177)163-40-20-22-86(163)124(206)140-51-94(173)142-66(17)106(188)137-52-96(175)146-84(56-165)122(204)157-81(46-62(9)10)119(201)152-75(27-34-90(133)169)128(210)164-41-21-23-87(164)125(207)160-78(43-59(3)4)116(198)144-68(19)108(190)154-79(44-60(5)6)117(199)149-70(29-37-100(180)181)110(192)139-53-97(176)147-85(57-166)123(205)158-82(47-63(11)12)120(202)153-76(129(211)212)28-35-91(134)170/h58-87,104-105,165-166H,20-57,130H2,1-19H3,(H2,131,167)(H2,132,168)(H2,133,169)(H2,134,170)(H,135,172)(H,136,171)(H,137,188)(H,138,193)(H,139,192)(H,140,206)(H,141,208)(H,142,173)(H,143,191)(H,144,198)(H,145,174)(H,146,175)(H,147,176)(H,148,189)(H,149,199)(H,150,200)(H,151,209)(H,152,201)(H,153,202)(H,154,190)(H,155,195)(H,156,203)(H,157,204)(H,158,205)(H,159,194)(H,160,207)(H,161,197)(H,162,196)(H,178,179)(H,180,181)(H,182,183)(H,184,185)(H,186,187)(H,211,212)/t66-,67-,68-,69-,70-,71-,72-,73-,74-,75-,76-,77-,78-,79-,80-,81-,82-,83-,84-,85-,86-,87-,104-,105-/m0/s1
• Clé InChI: VOUAQYXWVJDEQY-QENPJCQMSA-N

Description

Description générale

C-peptide, also known as the connecting peptide, is a 31-amino-acid polypeptide connecting insulin′s A-chain to its B-chain in the proinsulin molecule. Measurement of C-peptide blood serum levels can be used to distinguish between diabetes or hypoglycemia conditions with similar clinical features. This certified Snap-N-Spike^® solution of the fully-intact c-peptide protein is suitable for use as starting material in calibrators and controls in LC-MS/MS c-peptide testing methods.

This certified reference material (CRM) is a primary standard. It is traceable to the SI and higher order standards from National Institute of Standards and Technology (NIST) through an unbroken chain of comparisons. This C-Peptide (human) acetate salt is available as a solution of a pure substance in phosphate buffered saline with a pH of 7.4.

Application

C-Peptide solution is suitable for analytical and R&D applications for in vitro identification, calibration, and quantification.

Caractéristiques et avantages

• The total C-Peptide content is quantitatively determined using amino acid analysis (AAA) and HPLC/UV/MS, including unmodified, isomers, and pyroglu species, establishing traceability through the calibration of certification techniques.
• Each raw material used in the preparation of this standard has undergone thorough identification and characterization using multiple analytical techniques.
• The gravimetric preparation of this standard follows ISO 17025 requirements, utilizing qualified and calibrated balances.
• Fill volume conformity is ensured throughout the dispensing process by gravimetric verification using qualified and calibrated balances.
• Long-term stability under freezer storage (-10 °C to -25 °C) conditions has been evaluated.

Notes préparatoires

• Thaw the product in the refrigerator or at room temperature.
• Ensure thorough mixing before use.
• Avoid refreezing the product once it has thawed.
• For accurate results, quantitatively transfer the desired volume using established good laboratory practices.
• Use the transferred product to spike into the matrix or dilute it to achieve the desired concentration.

Autres remarques

This product′s purpose is for testing. THIS PRODUCT IS NOT INTENDED FOR HUMAN OR THERAPEUTIC USE. For comprehensive details regarding the nature of any hazards and recommended precautions, kindly refer to the safety data sheet.

Informations légales

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Informations sur la sécurité

• Code de la classe de stockage: 12 - Non Combustible Liquids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable