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840101C

Avanti

Egg PA

Avanti Research™ - A Croda Brand

Synonyme(s) :

L-α-phosphatidic acid (Egg, Chicken) (sodium salt)

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About This Item

Numéro CAS:
383907-53-7
Code UNSPSC :
12352211
Nomenclature NACRES :
NA.25

Pureté

>99% (TLC)

Forme

liquid

Conditionnement

pkg of 1 × 2.5 mL (840101C-25mg)

Fabricant/nom de marque

Avanti Research™ - A Croda Brand

Concentration

10 mg/mL (840101C-25mg)

Type de lipide

phosphoglycerides

Conditions d'expédition

dry ice

Température de stockage

−20°C

InChI

1S/C37H71O8P.Na/c1-3-5-7-9-11-13-15-17-18-20-22-24-26-28-30-32-37(39)45-35(34-44-46(40,41)42)33-43-36(38)31-29-27-25-23-21-19-16-14-12-10-8-6-4-2;/h17-18,35H,3-16,19-34H2,1-2H3,(H2,40,41,42);/q;+1/p-1/b18-17-;/t35-;/m1./s1

Clé InChI

PPYXMAJBOKWTQX-RYRMQHSSSA-M

Description générale

Phosphatidic acid (PA) is synthesized by the action of phospholipase D (PLD) on glycerophospholipids and by phosphorylation of diacylglycerol (DAG) by DAG kinase.

Application

Egg PA has been used in SEIPEN binding studies. It is suitable for use in the preparation of liposomes and to deduce different species of phosphatidic acid from egg by liquid chromatography-mass spectroscopy (LC-MS) and least squares spectral resolution (LSSR) analysis.

Actions biochimiques/physiologiques

Phosphatidic acid (PA) contributes to membrane biogenesis by involving in the synthesis of glycerophospholipids like phosphatidylcholine, phosphatidylethanolamine, phosphatidylinositol and phosphatidylserine. PA is implicated in cell signaling.

Conditionnement

5 mL Clear Glass Sealed Ampule (840101C-25mg)

Informations légales

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Pictogrammes

Skull and crossbonesHealth hazard
GHS06,GHS08

Mention d'avertissement

Danger

Classification des risques

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

Organes cibles

Central nervous system, Liver,Kidney

Classe de danger pour l'eau (WGK)

WGK 3

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Brain Lipids in Synaptic Function and Neurological Disease: Clues to Innovative Therapeutic Strategies for Brain Disorders (2015)
The lipid binding pleckstrin homology domain in UNC-104 kinesin is necessary for synaptic vesicle transport in Caenorhabditis elegans
Klopfenstein DR and Vale RD
Molecular Biology of the Cell, 15(8), 3729-3739 (2004)
Extension of least squares spectral resolution algorithm to high-resolution lipidomics data
Zeng YX, et al.
Analytica Chimica Acta, 914(8), 35-46 (2016)
Xianping Li et al.
Infection and immunity, 80(1), 429-440 (2011-11-16)
Aspergillus fumigatus is the most prevalent airborne fungal pathogen that induces serious infections in immunocompromised patients. Phospholipases are key enzymes in pathogenic fungi that cleave host phospholipids, resulting in membrane destabilization and host cell penetration. However, knowledge of the impact
Meygal Kahana et al.
Molecular psychiatry (2020-05-07)
Delivery of drugs into the brain is poor due to the blood brain barrier (BBB). This study describes the development of a novel liposome-based brain-targeting drug delivery system. The liposomes incorporate a diacylglycerol moiety coupled through a linker to a
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