W225207

β-Caryophyllene

≥80%, FCC, FG

• Synonyme(s) : (−)-trans-Caryophyllene, trans-(1R,9S)-8-Methylene-4,11,11-trimethylbicyclo[7.2.0]undec-4-ene
• Formule empirique (notation de Hill): C₁₅H₂₄
• Numéro CAS: 87-44-5
• Poids moléculaire : 204.35
• Numéro FEMA: 2252
• Numéro Beilstein : 2044564
• Numéro CE : 201-746-1
• Conseil de l'Europe Nº : 2618
• Numéro MDL: MFCD00075925
• Code UNSPSC : 12164502
• ID de substance PubChem : 24900952
• Numéro Flavis : 1.007
• Nomenclature NACRES : NA.21

Propriétés

• Source biologique: synthetic
• Niveau de qualité: 400
• Qualité: FG; Fragrance grade; Halal; Kosher
• Agence: follows IFRA guidelines; meets purity specifications of JECFA
• Conformité réglementaire: EU Regulation 1223/2009; EU Regulation 1334/2008 & 178/2002; FCC; FDA 21 CFR 117; FDA 21 CFR 172.515
• Pureté: ≥80%
• Activité optique: [α]23/D −7.5°, neat
• Composition: contains β-Caryophyllene
• Indice de réfraction: n20/D 1.5 (lit.)
• Point d'ébullition: 129-130 °C/14 mmHg (lit.)
• Densité: 0.901 g/mL at 25 °C (lit.)
• Application(s): flavors and fragrances
• Documentation: see Safety & Documentation for available documents
• Allergène alimentaire: no known allergens
• Allergène de parfum: β-caryophyllene (ox.)
• Propriétés organoleptiques: spicy; woody
• Chaîne SMILES: C\C1=C/CCC(=C)[C@H]2CC(C)(C)[C@@H]2CC1
• InChI: 1S/C15H24/c1-11-6-5-7-12(2)13-10-15(3,4)14(13)9-8-11/h6,13-14H,2,5,7-10H2,1,3-4H3/b11-6+/t13-,14-/m1/s1
• Clé InChI: NPNUFJAVOOONJE-GFUGXAQUSA-N

Description

Description générale

β;-Caryophyllene is a volatile sesquiterpene compound that can be used as a flavoring agent. It is one of the major volatile organic compounds in Eugenia caryophyllata essential oil, Psidium guajava L. leaves, Arabidopsis thaliana flowers and Artemisia annua L. aerial parts.

Application

• Essential Oil Constituents as Anti-Inflammatory and Neuroprotective Agents: An Insight through Microglia Modulation.: ß-Caryophyllene shows significant potential as an anti-inflammatory and neuroprotective agent by modulating microglia, which plays a crucial role in neuroinflammation (Stojanovic et al., 2024) (Stojanovic et al., 2024).


• Synergistic Antinociceptive Effect of ß-Caryophyllene Oxide in Combination with Paracetamol, and the Corresponding Gastroprotective Activity.: This research demonstrates that ß-caryophyllene oxide, when combined with paracetamol, has enhanced antinociceptive effects and provides gastroprotection (Espinosa-Juárez et al., 2024) (Espinosa-Juárez et al., 2024).


• Consumption of ß-Caryophyllene Increases the Mating Success of Bactrocera zonata Males (Diptera: Tephritidae).: The study explores how ß-caryophyllene consumption boosts the mating success of male fruit flies, indicating its potential applications in pest control strategies (Ul Haq et al., 2024) (Ul Haq et al., 2024).


• Development of ophthalmic nanoemulsions of ß-caryophyllene for the treatment of Acanthamoeba keratitis.: This research focuses on creating nanoemulsions containing ß-caryophyllene for treating Acanthamoeba keratitis, demonstrating its potential in ophthalmic therapies (Santos Porto et al., 2024) (Santos Porto et al., 2024).

Informations sur la sécurité

• Pictogrammes: GHS08,GHS07
• Mention d'avertissement: Danger
• Mentions de danger: H304,H317
• Conseils de prudence: P261 - P272 - P280 - P301 + P310 - P302 + P352 - P331
• Classification des risques: Asp. Tox. 1 - Skin Sens. 1B
• Code de la classe de stockage: 10 - Combustible liquids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): 221.9 °F - closed cup
• Point d'éclair (°C): 105.5 °C - closed cup
• Équipement de protection individuelle: Eyeshields, Gloves