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E45309

Sigma-Aldrich

Ethyl phenylpropiolate

98%

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About This Item

Formule linéaire :
C6H5C≡CCOOC2H5
Numéro CAS:
2216-94-6
Poids moléculaire :
174.20
Beilstein:
639637
Numéro CE :
218-703-8
Numéro MDL:
MFCD00009185
Code UNSPSC :
12352100
ID de substance PubChem :
24894561
Nomenclature NACRES :
NA.22
Le tarif et la disponibilité ne sont pas disponibles actuellement.

Essai

98%

Forme

liquid

Indice de réfraction

n20/D 1.552 (lit.)

pb

260-270 °C (lit.)

Densité

1.055 g/mL at 25 °C (lit.)

Température de stockage

2-8°C

Chaîne SMILES 

CCOC(=O)C#Cc1ccccc1

InChI

1S/C11H10O2/c1-2-13-11(12)9-8-10-6-4-3-5-7-10/h3-7H,2H2,1H3

Clé InChI

ACJOYTKWHPEIHW-UHFFFAOYSA-N

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Code de la classe de stockage

10 - Combustible liquids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Gloves

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Certificats d'analyse (COA)

Lot/Batch Number
SDBB1902
STBK5840
STBJ2546
STBH2949
S16570V

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Methyl propiolate 99%

Sigma-Aldrich

171859

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4-Phenyl-3-butyn-2-ol 97%

Sigma-Aldrich

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Cimetidine

Sigma-Aldrich

C4522

Cimetidine

S K Gilmour et al.
Carcinogenesis, 13(1), 51-56 (1992-01-01)
Single applications of 12-O-tetradecanoylphorbol-13-acetate (TPA), mezerein or ethyl phenylpropriolate (EPP) to mouse skin at appropriate doses cause similar degrees of hyperplasia and comparable levels of induction of epidermal ornithine decarboxylase (ODC) activity. Multiple (n = 5) treatments with these agents
E Patrick et al.
Toxicology and applied pharmacology, 81(3 Pt 1), 476-490 (1985-12-01)
The possibility that chemicals induce skin irritation by multiple mechanisms was studied in laboratory mice. The time course and dose response to topical application of phenol, croton oil, benzalkonium chloride, ethyl phenylpropiolate (EPP), and methyl salicylate were compared. The responses
B H Shearer et al.
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, 23(4), 149-155 (1994-04-01)
The effects of four different hyperplastic agents and of the carcinogen DMBA on cytokeratin expression in hamster cheek pouch epithelia were compared. Reversible hyperplasia was produced by the application of either oil of turpentine, vitamin A or TPA. No hyperplastic
C E Weeks et al.
Proceedings of the National Academy of Sciences of the United States of America, 79(19), 6028-6032 (1982-10-01)
The role of ornithine decarboxylase (OrnDCase, EC 4.1.1.17) and of the polyamines [putrescine (Put), spermidine (Spd), and spermine (Spm)] in mouse skin tumor promotion was investigated by the use of alpha-difluoromethylornithine (CHF2-Orn), an enzyme-activated irreversible inhibitor of OrnDCase. 12-O-Tetradecanoylphorbol 13-acetate
C S Baxter et al.
Carcinogenesis, 10(10), 1855-1861 (1989-10-01)
Responses of various cells of the epidermis and dermis to topically applied agents have been implicated in the mechanism of multistage mouse tumorigenesis. These responses have been discussed almost entirely in the context of a single promoter treatment, although tumor
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