745405

Sodium 1,1-difluoroethanesulfinate

• Synonyme(s) : Baran DFES Reagent, Baran Difluoroethylation Reagent, DFES-Na Reagent, Sodium 1,1-difluoroethylsulfinate
• Formule empirique (notation de Hill): C₂H₃F₂NaO₂S
• Numéro CAS: 1422738-67-7
• Poids moléculaire : 152.10
• Numéro MDL: MFCD23704444
• Code UNSPSC : 12352001
• ID de substance PubChem : 329764978
• Nomenclature NACRES : NA.22

Propriétés

• Forme: solid
• Niveau de qualité: 100
• Capacité de réaction: reaction type: C-C Bond Formation; reaction type: Fluorinations
• Pertinence de la réaction: reagent type: catalyst; reaction type: C-H Activation; reagent type: diversification reagent
• Pf: >300 °C
• Chaîne SMILES: [Na+].CC(F)(F)S([O-])=O
• InChI: 1S/C2H4F2O2S.Na/c1-2(3,4)7(5)6;/h1H3,(H,5,6);/q;+1/p-1
• Clé InChI: YAUVUSSCQUHHFC-UHFFFAOYSA-M

Description

Application

DFES-Na provides a direct approach to fluorinated heteroarylether bioisosteres by appending a 1,1-difluoroethyl group operationally simple and robust protocol. This reagent was developed by the Baran Group and is one of several reagents for the direct alkylation of heterocycles.

Learn More at the Professor and Product Portal of Professor Phil S. Baran.
Baran Diversinates(TM) Lead Diversification and Metabolism Prediction Flyer

Liaison

Frequently Asked Questions are available for this Product.

Autres remarques

Previously sold under product number L511404

Informations sur la sécurité

• Pictogrammes: GHS07
• Mention d'avertissement: Warning
• Mentions de danger: H315,H319,H335
• Conseils de prudence: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Classification des risques: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Organes cibles: Respiratory system
• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable