404411

(R,R)-(−)-N,N′-Bis(3,5-di-tert-butylsalicylidene)-1,2-cyclohexanediamine

98%

• Synonyme(s) : (R,R)-Jacobsen’s ligand
• Formule linéaire : [[(CH₃)₃C]₂C₆H₂-2-(OH)CH=N]₂C₆H₁₀
• Numéro CAS: 135616-40-9
• Poids moléculaire : 546.83
• Numéro Beilstein : 5464823
• Numéro MDL: MFCD00191800
• Code UNSPSC : 12352116
• ID de substance PubChem : 24865244
• Nomenclature NACRES : NA.22

Propriétés

• Niveau de qualité: 100
• Pureté: 98%
• Forme: solid
• Activité optique: [α]20/D −315±15°, c = 1 in methylene chloride
• Pf: 205-207 °C (lit.)
• Chaîne SMILES: CC(C)(C)c1cc(\C=N\[C@@H]2CCCC[C@H]2\N=C\c3cc(cc(c3O)C(C)(C)C)C(C)(C)C)c(O)c(c1)C(C)(C)C
• InChI: 1S/C36H54N2O2/c1-33(2,3)25-17-23(31(39)27(19-25)35(7,8)9)21-37-29-15-13-14-16-30(29)38-22-24-18-26(34(4,5)6)20-28(32(24)40)36(10,11)12/h17-22,29-30,39-40H,13-16H2,1-12H3/b37-21+,38-22+/t29-,30-/m1/s1
• Clé InChI: FYNXDGNCEBQLGC-LQWPWIHBSA-N

Description

Application

Amylases from Aspergillus oryzae are used to prevent staling in the baking industry, clarify haze from fruit juices and alcoholic beverages, and produce glucose and maltose syrup products.

Versatile ligand for asymmetric catalysis. Ligand used for preparing Jacobsen′s catalyst suitable for enantioselective epoxidation of olefins lacking functional groups.

Lipases are used industrially for the resolution of chiral compounds and the transesterification production of biodiesel.

Actions biochimiques/physiologiques

α-amylase catalyzes the hydrolysis of internal α-1,4-O-glycosidic bonds in starches to release α-anomeric sugars.

Lipases catalyze the hydrolysis of triacylglycerols into glycerol and free fatty acids.

Informations légales

Manufactured under license by Sterling Pharma Solutions Limited, using Jacobsen HKR technology.

Informations sur la sécurité

• Pictogrammes: GHS07
• Mention d'avertissement: Warning
• Mentions de danger: H315,H319,H335
• Conseils de prudence: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Classification des risques: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Organes cibles: Respiratory system
• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: dust mask type N95 (US), Eyeshields, Gloves