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890850O

Avanti

18:1 DAP

Avanti Research - A Croda Brand

Synonym(s):

1,2-dioleoyl-3-dimethylammonium-propane (DODAP)

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About This Item

Empirical Formula (Hill Notation):
C41H77NO4
CAS Number:
Molecular Weight:
648.05
UNSPSC Code:
12352211
NACRES:
NA.25

Pricing and availability is not currently available.

form

liquid

packaging

pkg of 2 × 100 mg (890850O-200mg)
pkg of 1 × 25 mg (890850O-25mg)

manufacturer/tradename

Avanti Research - A Croda Brand

lipid type

cationic lipids
transfection

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H]C(CN(C)C)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCC/C=C\CCCCCCCC)=O

General description

18:1 DAP is a cationic lipid, used for the preparation of cationic liposomes.[1]

Application

18:1 DAP is suitable for:
  • as a component of lipid bilayers[2]
  • in the formulation of stable nucleic acid lipid vesicles[3]
  • in the preparation and physicochemical characterization of antisense oligodeoxyribonucleotide (ODN)-containing folate (FA)-targeted or non-targeted liposomes[1]

Packaging

5 mL Clear Glass Sealed Ampule (890850O-200mg)
5 mL Clear Glass Sealed Ampule (890850O-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class Code

10 - Combustible liquids

WGK

WGK 3


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Transferrin-conjugated SNALPs encapsulating 2?-O-methylated miR-34a for the treatment of multiple myeloma
Scognamiglio I, et al.
BioMed Research International, 2014 (2014)
Preparation and in-vitro evaluation of an antisense-containing cationic liposome against non-small cell lung cancer: a comparative preparation study
Saffari M, et al.
Iranian Journal of Pharmaceutical Research : IJPR, 12(Suppl), 3-3 (2013)
Nonequilibrium adhesion patterns at lipid bilayer junctions
Parthasarathy R, et al.
The Journal of Physical Chemistry B, 108(2), 649-657 (2004)
Qiang Cheng et al.
Nature nanotechnology, 15(4), 313-320 (2020-04-07)
CRISPR-Cas gene editing and messenger RNA-based protein replacement therapy hold tremendous potential to effectively treat disease-causing mutations with diverse cellular origin. However, it is currently impossible to rationally design nanoparticles that selectively target specific tissues. Here, we report a strategy

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