42358

Dioctadecylamine

≥99.0% (NT)

• Synonym(s): DODA, Distearylamine
• Linear Formula: [CH₃(CH₂)₁₇]₂NH
• CAS Number: 112-99-2
• Molecular Weight: 521.99
• Beilstein: 1801688
• EC Number: 204-020-2
• MDL number: MFCD00048494
• UNSPSC Code: 12352100
• PubChem Substance ID: 57650109
• NACRES: NA.22

Properties

• Assay: ≥99.0% (NT)
• mp: 71-73 °C
• solubility: water: soluble(lit.)
• functional group: amine
• SMILES string: CCCCCCCCCCCCCCCCCCNCCCCCCCCCCCCCCCCCC
• InChI: 1S/C36H75N/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-35-37-36-34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2/h37H,3-36H2,1-2H3
• InChI key: HKUFIYBZNQSHQS-UHFFFAOYSA-N

Description

General description

Dioctadecylamine (DODA), a secondary amine, is a fatty amine derivative. Its biodegradation potential has been assessed. It has been observed that in aqueous medium DODA self organizes into plate like structures. Its partial charge distribution as a function of its conformation has been analyzed. The phase diagram of dioctadecylamine Langmuir monolayers has been determined and investigations show it does not form a monolayer above pH 3.9. DODA has been utilized in forming liposomes, cationic lipids or lipid chelating agents.

Application

Dioctadecylamine (DODA) is suitable reagent used in the synthesis of the following:

• Dioctadecylamine-BCN (bicyclo[6.1.0]nonyne) conjugate.
• Lipid derivatives of bisethylnorspermine (BSP).
• Functional VP (N-vinylpyrrolidone ) polymers.

It may be used in the following studies:

• As a reactant in the synthesis of 4,4′-azobis(4-cyano-N,N-dioctadecyl)pentanamide (DODA-501) by reacting with disuccinimidyl 4,4′-azobis(4-cyanovalerate).
• As a reagent in the synthesis of dioctadecyl heptapeptides.
• As a phase transfer and stabilizer agent for gold nanoparticles (AuNPs) in non-polar solvent.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H315,H319,H335
• Precautionary Statements: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves