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Key Documents

I0631

Sigma-Aldrich

Imidodiphosphate sodium salt

≥97%

Synonym(s):

Tetrasodium imidodiphosphate

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About This Item

Linear Formula:
HNO6P2Na4
CAS Number:
Molecular Weight:
264.92
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Quality Level

Assay

≥97%

storage temp.

2-8°C

SMILES string

O=P([O-])([O-])NP([O-])([O-])=O.[Na+].[Na+].[Na+].[Na+]

InChI

1S/H5NO6P2.4Na/c2-8(3,4)1-9(5,6)7;;;;/h(H5,1,2,3,4,5,6,7);;;;/q;4*+1/p-4

InChI key

KDZOOFFPQVQSQG-UHFFFAOYSA-J

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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George D Markham et al.
Biochemistry, 43(12), 3415-3425 (2004-03-24)
S-Adenosylmethionine synthetase (ATP: L-methionine S-adenosyltransferase) catalyzes a two-step reaction in which tripolyphosphate (PPPi) is a tightly bound intermediate. Diimidotriphosphate (O(3)P-NH-PO(2)-NH-PO(3); PNPNP), a non-hydrolyzable analogue of PPPi, is the most potent known inhibitor of AdoMet synthetase with a K(i) of 2
A B Zyryanov et al.
Biochemistry. Biokhimiia, 70(8), 908-912 (2005-10-11)
Imidodiphosphate (the pyrophosphate analog containing a nitrogen atom in the bridge position instead of oxygen) is a potent inhibitor of family II pyrophosphatases from Streptococcus mutans and Streptococcus gordonii (inhibition constant Ki approximately 10 microM), which is slowly hydrolyzed by
N F Zakirova et al.
Bioorganicheskaia khimiia, 31(1), 96-102 (2005-03-25)
The preparation conditions for dichlorophosphinylphosphorimidic trichloride were optimized. It was used in the synthesis of esters of imidodiphosphoric acid. The interaction of the trichloride with amines resulted in the corresponding amidodiphosphates rather than in the expected amides of imidodiphosphoric acid.
Anna M Rydzik et al.
Bioorganic & medicinal chemistry, 20(5), 1699-1710 (2012-02-10)
We describe synthesis and properties of eight dinucleotide mRNA 5' cap analogs containing imidodiphosphate moiety within 5',5'-tri- or tetraphosphate bridge (NH-analogs). The compounds were obtained by coupling an appropriate nucleoside 5'-imidodiphosphate with nucleotide P-imidazolide mediated by divalent metal chloride in
T Rozovskaya et al.
FEBS letters, 247(2), 289-292 (1989-04-24)
It is demonstrated here that rat liver DNA polymerase beta catalyzes the pyrophosphorolysis reaction with pyrophosphate (PPi) and its analogues. The substrate specificity of the PPi-binding site of several DNA polymerases was investigated. It was discovered that the ability of

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