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A5707

Sigma-Aldrich

Argininosuccinic acid disodium salt hydrate

≥80%

Synonym(s):

Sodium N-[[[(4S)-4-amino-4-carboxybutyl]amino]iminomethyl]-L-aspartate (2:1)

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About This Item

Empirical Formula (Hill Notation):
C10H16N4Na2O6 · xH2O
CAS Number:
918149-29-8
Molecular Weight:
334.24 (anhydrous basis)
MDL number:
MFCD11656132
UNSPSC Code:
12352100
PubChem Substance ID:
57653861
NACRES:
NA.22

Quality Level

200

Assay

≥80%

form

powder

storage temp.

−20°C

SMILES string

O.[Na+].[Na+].N[C@@H](CCCNC(=N)N[C@@H](CC([O-])=O)C(O)=O)C([O-])=O

InChI

1S/C10H18N4O6.2Na.H2O/c11-5(8(17)18)2-1-3-13-10(12)14-6(9(19)20)4-7(15)16;;;/h5-6H,1-4,11H2,(H,15,16)(H,17,18)(H,19,20)(H3,12,13,14);;;1H2/q;2*+1;/p-2/t5-,6-;;;/m0.../s1

InChI key

UCTAVRCIKYVVFI-VDBFCSKJSA-L

Application

Argininosuccinic acid disodium salt hydrate has been used in the spectrophotometric measurement of argininosuccinate lyase (ASL) enzymatic activity in cell extracts.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
0000334088
0000298448
0000298428
0000319498
0000319485

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Liyan Hu et al.
The Journal of biological chemistry, 288(48), 34599-34611 (2013-10-19)
Argininosuccinic aciduria (ASA) is an autosomal recessive urea cycle disorder caused by deficiency of argininosuccinate lyase (ASL) with a wide clinical spectrum from asymptomatic to severe hyperammonemic neonatal onset life-threatening courses. We investigated the role of ASL transcript variants in

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