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202339

Sigma-Aldrich

Poly(propylene glycol)

average Mn ~2,000

Synonym(s):

PPG, Poly(propylene oxide)

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About This Item

Linear Formula:
H[OCH(CH3)CH2]nOH
CAS Number:
25322-69-4
MDL number:
MFCD00084446
UNSPSC Code:
12162002
PubChem Substance ID:
24852056
NACRES:
NA.23

vapor density

>1 (vs air)

Quality Level

200

vapor pressure

<0.01 mmHg ( 20 °C)

mol wt

average Mn ~2,000

contains

130-190 ppm proprietary phenolic antioxidant

refractive index

n20/D 1.451

viscosity

300 cSt(25 °C)(lit.)

hydroxyl value

56 mg KOH/g

density

1.005 g/mL at 25 °C

SMILES string

CC(O)CO

InChI

1S/C6H14O3/c1-5(8)4-9-6(2)3-7/h5-8H,3-4H2,1-2H3

InChI key

DUFKCOQISQKSAV-UHFFFAOYSA-N

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General description

Poly(propylene glycol) (PPG) is a polyether. It is prepared by ring-opening polymerization of propylene oxide. PPG is less toxic and used as a dispersant in leather finishing, as a surfactant, wetting agent, and in drug formulations.

Application

Poly(propylene glycol) can be used as a:
  • Corrosion inhibitor for mild steel in acid solution.
  • Starting material to synthesize epoxy resin/polyurethane hybrid networks via frontal polymerization.
It can also be used to prepare poly(PEG/PPG/PTMC urethane) thermogels for sustained release of doxorubicin.

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

445.0 °F - closed cup

Flash Point(C)

229.44 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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James E Hudson et al.
Tissue engineering. Part A, 17(17-18), 2279-2289 (2011-05-06)
Tissue engineering approaches are currently being investigated for the restoration of myocardial function in heart failure patients, most commonly by combining cells with a substrate to form myocardial-like constructs (MCs). The final properties of these constructs are dependant on the
Elisa Campos et al.
Colloids and surfaces. B, Biointerfaces, 88(1), 477-482 (2011-08-09)
Bi-soft segmented poly(ester urethane urea) microparticles were prepared and characterized aiming a biomedical application. Two different formulations were developed, using poly(propylene glycol), tolylene 2,4-diisocyanate terminated pre-polymer (TDI) and poly(propylene oxide)-based tri-isocyanated terminated pre-polymer (TI). A second soft segment was included
Daimei Chen et al.
Journal of hazardous materials, 235-236, 186-193 (2012-08-14)
TiO(2) pillared clay materials were prepared by montmorillonite (Mt) and acidic solutions of hydrolyzed Ti alkoxides in the presence of high-molecular-weight polyoxypropylene (POP)-backboned di-quaternary salts (POP). The as-prepared materials were characterized by means of XRD, FTIR, TG-DTA, XRF, specific surface
Celeste R Brennecka et al.
Journal of biomedical materials research. Part B, Applied biomaterials, 100(5), 1298-1309 (2012-04-20)
This study examines the in vitro characteristics of a crosslinking polymer system for cerebral aneurysm embolization. The polymeric material is composed of poly(propylene glycol)diacrylate (PPODA) and pentaerythritol tetrakis(3-mercaptopropionate) (QT), formulated with the liquid contrast agents Conray™ or Omnipaque™ 300. The
Flávia Chiva Carvalho et al.
Journal of biomedical nanotechnology, 8(2), 280-289 (2012-04-21)
In the last few decades, nanotechnology has led to an advance in the development of topical drug delivery. Nanostructured drug delivery systems enable the compartmentalization of drugs in restricted environments, modifying the release profile and maintaining the required drug concentration
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