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412325

Sigma-Aldrich

Poly(ethylene glycol)-block-poly(propylene glycol)-block-poly(ethylene glycol)

average Mn ~8,400

Synonym(s):

Pluronic® F-68 LF Pastille, PEG-PPG-PEG

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About This Item

CAS Number:
9003-11-6
MDL number:
MFCD00082049
UNSPSC Code:
12352112
PubChem Substance ID:
24865804
NACRES:
NA.23
Pricing and availability is not currently available.

vapor density

>1 (vs air)

vapor pressure

<0.3 mmHg ( 20 °C)

form

beads

mol wt

average Mn ~8,400

composition

PEG, 80 wt. %

surface tension

50 dyn/cm, 25 °C, 0.1 wt. % in H2O

viscosity

1,000 cP(77 °C, Brookfield)(lit.)

transition temp

cloud point >100 °C (1 wt. % aqueous solution)
Tm 52 °C

density

1.06 g/mL at 25 °C

HLB

>24.0

SMILES string

O2C(C2)C.O1CC1

InChI

1S/C3H6O.C2H4O/c1-3-2-4-3;1-2-3-1/h3H,2H2,1H3;1-2H2

InChI key

RVGRUAULSDPKGF-UHFFFAOYSA-N

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Application

Hard and soft surface cleaners, defoamers in coatings and water treatment. Lubricant in metal working, anti-foaming aid and extender for linear and cross-linked polyesters and polyurethanes.

Features and Benefits

Surface active material whose properties are dependent on the hydrophilic (EO)/hydrophobic (PO) ratio. High EO content gives better o/w stabilizers.

Physical form

Terminal primary dihydroxy-functional oligomer.

Legal Information

Pluronic is a registered trademark of BASF

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
MKCV4467
MKCR4188
MKCL6608
MKCF2543
MKCK4853

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Sean P Cleary et al.
The Analyst, 145(13), 4688-4697 (2020-05-28)
Native electrospray mass spectrometry is a powerful method for determining the native stoichiometry of many polydisperse multi-subunit biological complexes, including multi-subunit protein complexes and lipid-bound transmembrane proteins. However, when polydispersity results from incorporation of multiple copies of two or more
Céline Durand-Gasselin et al.
Langmuir : the ACS journal of surfaces and colloids, 27(20), 12329-12335 (2011-09-29)
Aggregation of thermosensitive polymer-coated gold nanoparticles was performed in aqueous solution in the presence of a triblock copolymer poly(ethylene oxide)-block-poly(propylene oxide)-block-poly(ethylene oxide) (Pluronic P123, PEO(20)-PPO(68)-PEO(20)). The gold nanoparticles, AuNPs, which are covered by thermosensitive statistical copolymers poly(EO(x)-st-PO(y)), aggregate when the
V K Zhalimov et al.
Biofizika, 57(2), 308-316 (2012-05-19)
It has been shown that sorption of most proteins with the molecular weight lower than 200 kDa from human blood plasma on the surface of perfluorocarbon emulsion, stabilized with proxanol 268, is mainly based on hydrophobic interaction, whereas sorption of
Liyan Zhao et al.
Colloids and surfaces. B, Biointerfaces, 97, 101-108 (2012-05-23)
In this study, curcumin (Cur) loaded mixed micelles (Cur-PF), composed of Pluronic P123 (P123) and Pluronic F68 (F68), was prepared using the thin-film hydration method and evaluated in vitro. The preparation process was optimized with a central composite design (CCD).
Laurien Buitinga et al.
Clinical and experimental rheumatology, 29(5), 783-789 (2011-10-04)
The Time Trade-Off (TTO) is an instrument used for valuing health-related quality of life. This study evaluated the test-retest reliability of a computer TTO in rheumatoid arthritis (RA), and compared the computer with the interview TTO regarding feasibility and agreement.
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Questions

1–2 of 2 Questions  

  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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