SUPELCOSIL ABZ+Plus columns offer both high deactivation and unique selectivity. Deactivated silica particles of very narrow particle size distribution ensure high efficiency with low back pressure. After bonding and endcapping reactions, the ABZ+Plus phase effectively shields unreacted silanol groups on the silica, preventing them from interacting with most analytes, and provides symmetric peaks regardless of an analyte′s functionality. The phase also allows you to use low ionic strength buffers without having to add an ion-suppressing modifier. ABZ+Plus enables you to use simple mobile phases when analyzing the most difficult compounds; acids, strongly basic compounds, and zwitterions. suitable for L60 per USP
Features and Benefits
• High efficiency for polar, nonpolar, and charged analytes • Symmetric peaks for the most reactive compounds • Unique selectivity for polar and charged compounds
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Legal Information
SUPELCOSIL is a trademark of Sigma-Aldrich Co. LLC
Journal of chromatography. B, Biomedical sciences and applications, 705(1), 97-103 (1998-03-14)
A rapid and simple high-performance liquid chromatographic (HPLC) method with amperometric detection has been developed for the quantitation of labetalol in urine. The chromatography was performed at 30 degrees C using a reversed-phase column with a base deactivated silica stationary
Journal of chromatography. B, Biomedical sciences and applications, 703(1-2), 129-138 (1998-02-03)
A sensitive, specific and precise HPLC-UV assay was developed to quantitate cocaine (COC) and its metabolites benzoylecgonine (BE), norcocaine (NC) and cocaethylene (CE) in rat plasma. After adding 50 microl of the internal standard solution (bupivacaine, 8 microg/ml) and 500
Journal of chromatography. A, 797(1-2), 221-226 (1998-05-16)
A reversed-phase high-performance liquid chromatographic method with electrochemical detection has been developed for the determination of buspirone from human plasma. The separation was carried out by using a Supelcosil ABZ+ plus C18 reversed-phase column and 0.05 M potassium dihydrogenphosphate (pH
A liquid-liquid extraction method using diethyl ether as organic solvent was optimized simultaneously for five 1,4-dihydropyridines (amlodipine, nitrendipine, felodipine, lacidipine and lercanidipine) belonging to the group of calcium channel blockers. Some experimental tools such as a full factorial design, a
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 810(1), 77-83 (2004-09-11)
Liquid chromatography with a column-switching technique was developed for simultaneous direct quantification of levofloxacin, gatifloxacin and moxifloxacin in human serum. Serum samples were injected on a LiChroCART 4-4 pre-column (PC) filled with a LiChrospher 100 RP-18, 5 microm where fluoroquinolones
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