SUPELCOSIL LC-DB phases are specially deactivated for basic compounds. These columns provide shorter retention, better peak shape, and higher efficiency for organic bases than can be obtained on other Type A silica reversed-phase columns.
Application
SUPELCOSIL™ LC-18-DB HPLC Column has been used for the separation of:
Analytes of pharmaceutical relevance during their analysis using LC in conjunction with principal component analysis (PCA).[1]
Loratadine in human plasma during its analysis by using HPLC combined with ultraviolet (UV) detection.[2]
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Legal Information
SUPELCOSIL is a trademark of Sigma-Aldrich Co. LLC
Determination of loratadine in human plasma by high-performance liquid chromatographic method with ultraviolet detection.
Kunicki PK.
Journal of Chromatography. B, Biomedical Sciences and Applications, 755(1-2), 331-335 (2001)
Chromatographic classification and comparison of commercially available reversed-phase liquid chromatographic columns using principal component analysis
Euerby MR and Petersson P
Journal of Chromatography A, 994(1-2), 13-36 (2003)
Aging is an independent risk factor for cardiovascular diseases, such as myocardial infarction due to ischemia-reperfusion injury (I/R) of the heart. Cytosolic thioredoxin (Trx) is a multifunctional redox protein which has antioxidant and protein disulfide reducing properties. We hypothesized that
Therapeutic drug monitoring, 23(2), 163-168 (2001-04-11)
Recipients of organ transplants remain particularly dependent on prednisolone as part of their maintenance immunosuppression. Despite this, the pharmacokinetics of prednisolone have never been fully characterized in these patients, and consequently dosing remains empirical. Accurate monitoring of prednisolone, its primary
Journal of pharmaceutical and biomedical analysis, 26(4), 637-650 (2001-08-23)
An LC/MS/MS method for the simultaneous determination of cilostazol, a quinolinone derivative, and three active metabolites, OPC-13015, OPC-13213, and OPC-13217, in human plasma was developed and validated. Cilostazol, its metabolites, and the internal standard, OPC-3930 were extracted from human plasma
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