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B7929

Sigma-Aldrich

Anti-Bim antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

Synonym(s):

Anti-BOD

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About This Item

MDL number:
MFCD02095895
UNSPSC Code:
12352203

biological source

rabbit

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

antigen 23 kDa

species reactivity

human, rat, mouse

technique(s)

immunohistochemistry: 20 μg/mL using human skin cancer cells
microarray: suitable
western blot: 1 μg/mL using A549 or K562 whole cell lysates

UniProt accession no.

O43521

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... BCL2L11(10018)
mouse ... Bcl2l11(12125)
rat ... Bcl2l11(64547)

Immunogen

synthetic peptide corresponding to amino acids 22-40 of human Bim (BOD). This sequence is identical in mouse and contains only one amino acid substitution in rat.

Physical form

Solution in phosphate buffered saline containing 0.02% sodium azide

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

12 - Non Combustible Liquids

WGK

nwg

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Violeta Gómez-Vicente et al.
The European journal of neuroscience, 24(4), 981-990 (2006-08-26)
Apoptosis of photoreceptor cells in the early postnatal period is a normal feature of mammalian retinal development. The role of mitochondria and caspases in the process has been well established; however, the identification of key apoptotic mediators still remains elusive.
P Geserick et al.
Cell death & disease, 5, e1412-e1412 (2014-09-12)
Tumour progression and therapy resistance in squamous cell carcinoma of the skin (SCC) is strongly associated with resistance to intrinsic mitochondrial apoptosis. We thus investigated the role of various anti-apoptotic Bcl-2 proteins for apoptosis protection in SCC using the BH3
Nina Stojcheva et al.
Oncotarget, 7(11), 12937-12950 (2016-02-18)
Glioblastoma is the most aggressive brain tumor in adults with a median survival below 12 months in population-based studies. The main reason for tumor recurrence and progression is constitutive or acquired resistance to the standard of care of surgical resection
Laura Elisa Buitrago-Molina et al.
Cellular and molecular gastroenterology and hepatology, 11(5), 1387-1404 (2021-01-24)
A coordinated stress and regenerative response is important after hepatocyte damage. Here, we investigate the phenotypes that result from genetic abrogation of individual components of the checkpoint kinase 2/transformation-related protein 53 (p53)/cyclin-dependent kinase inhibitor 1A (p21) pathway in a murine
Marc B Guerin et al.
Clinical & experimental ophthalmology, 39(3), 243-251 (2011-04-15)
This paper seeks to investigate differences between the neonatal and adult retinal ganglion cell populations to apoptotic death stimuli. DESIGN AND SAMPLES: In vitro and ex vivo paradigms involving P6 and P60 Sprague-Dawley rat retinal explants and retinal ganglion cells
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