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Y0000239

Celiprolol for peak identification

European Pharmacopoeia (EP) Reference Standard

Synonym(s):

Celiprolol hydrochloride

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About This Item

Empirical Formula (Hill Notation):
C20H33N3O4 · HCl
CAS Number:
57470-78-7
Molecular Weight:
415.95
MDL number:
MFCD00941500
UNSPSC Code:
41116107
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

celiprolol

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

InChI

1S/C20H33N3O4.ClH/c1-7-23(8-2)19(26)22-15-9-10-18(17(11-15)14(3)24)27-13-16(25)12-21-20(4,5)6;/h9-11,16,21,25H,7-8,12-13H2,1-6H3,(H,22,26);1H

InChI key

VKJHTUVLJYWAEY-UHFFFAOYSA-N

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Celiprolol for peak identification EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Jiangeng Huang et al.
International journal of pharmaceutics, 356(1-2), 351-353 (2008-02-05)
The aim of this work was to investigate the effects of pluronic F68 block copolymer on the P-gp-mediated transport of celiprolol (CEL) and CYP3A4-mediated formation of midazolam (MDZ) metabolite 1'-hydroxymidazolam. Over a range from 0.03 to 0.3%, pluronic F68 increased
En-Hui Yao et al.
American journal of hypertension, 21(9), 1062-1068 (2008-07-19)
Endothelial progenitor cells (EPCs) derived from bone marrow migrate to areas of endothelial damage and repair them. EPC function is impaired by oxidative stress. We examined the effects of an antioxidative beta1-adrenoceptor blocker on the number and function of EPCs
A Jamard et al.
Journal de gynecologie, obstetrique et biologie de la reproduction, 41(7), 676-678 (2012-04-24)
The Ehlers-Danlos syndrome (EDS) is a rare inheritable disease, characterised by a defect in collagen synthesis. Various types have been described and the type IV or vascular type is the most severe characterised by vascular, gastrointestinal and gynaecologic complications. We
Frédérique Sauvaget et al.
European journal of pharmacology, 644(1-3), 169-175 (2010-07-20)
We evaluated celiprolol-induced vasodilatation in aorta taken from 12-week-old spontaneously hypertensive rats (SHR) and the effect of AT(1) angiotensin II receptor antagonism on the vasodilatory action of celiprolol in Wistar Kyoto (WKY) rats and SHR. In WKY rats, the celiprolol-induced
Jean-Christophe Charniot et al.
Acta cardiologica, 61(6), 661-663 (2007-01-09)
Systemic lupus erythematosus can be idiopathic or drug-induced. Although a number of beta-blockers have been reported to induce a lupus-like syndrome, to the best of our knowledge, no such case has been described following celiprolol therapy. We diagnosed a lupus-like
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