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Sigma-Aldrich

Dodecamethylpentasiloxane

97%

Synonym(s):

1,1,1,3,3,5,5,7,7,9,9,9-Dodecamethylpentasiloxane, DC 200 Fluid 2

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About This Item

Linear Formula:
(CH3)3SiO[Si(CH3)2O]3Si(CH3)3
CAS Number:
141-63-9
Molecular Weight:
384.84
EC Number:
205-492-2
MDL number:
MFCD00039795
UNSPSC Code:
12352103
PubChem Substance ID:
24868328
NACRES:
NA.22

vapor pressure

<1 mmHg ( 20 °C)

Assay

97%

refractive index

n20/D 1.392 (lit.)

bp

230 °C (lit.)

mp

−81 °C (lit.)

density

0.875 g/mL at 25 °C (lit.)

SMILES string

C[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)C

InChI

1S/C12H36O4Si5/c1-17(2,3)13-19(7,8)15-21(11,12)16-20(9,10)14-18(4,5)6/h1-12H3

InChI key

FBZANXDWQAVSTQ-UHFFFAOYSA-N

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General description

Dodecamethylpentasiloxane is an organosilicon compound that is used as a reactant or as a solvent in organic synthesis. It is also used as a precursor compound to synthesize useful compounds, such as straight-chain linear polydimethylsiloxanes (PDMS), which are widely used in industrial applications such as coatings, adhesives, and elastomers.

Application

  • Adsorption Characteristics of Dodecamethylpentasiloxane from Landfill Leachate: This study investigates the adsorption behavior of dodecamethylpentasiloxane in municipal solid waste, crucial for environmental chemists and waste management specialists (Q Kong et al., 2022).
  • Toxicity of Silicone Oil: This research evaluates the cytotoxicity of liquid low molecular weight cyclosiloxanes including dodecamethylpentasiloxane, significant for drug discovery chemists considering silicone oil applications (Y Chen et al., 2021).
  • Bioaccumulation of Volatile Methylsiloxanes: Review of how volatile methylsiloxanes like dodecamethylpentasiloxane bioaccumulate in aquatic ecosystems, useful for environmental scientists and regulatory bodies (F Bernardo et al., 2022).
  • Solid MRI Contrast Agents: Describes the use of dodecamethylpentasiloxane as a contrast agent for in vivo oxygen sensing, relevant to biomedical research and materials science (VH Liu et al., 2014).
  • Effective Removal of Methyl Siloxane by Sewage Sludge Microbes: Discusses biodegradation of dodecamethylpentasiloxane, pertinent for environmental chemists and waste treatment research (Y Wang et al., 2019).

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

186.8 °F - closed cup

Flash Point(C)

86 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Danbi Lee et al.
Ecotoxicology and environmental safety, 182, 109457-109457 (2019-07-28)
Siloxanes have been used as chemical additives in various products since the 1940s. They are known to have potentially toxic effects, to be environmentally persistent, and to be bioaccumulative. Previous studies have reported high levels of siloxanes in various environmental
Zhen Cheng et al.
Environmental pollution (Barking, Essex : 1987), 271, 116128-116128 (2021-01-10)
Organosilicons are widely used in consumer products and are ubiquitous in living environments. However, there is little systemic information on this group of pollutants in ambient particles. This study proposes a novel untargeted strategy based mainly on the mass difference
Juan Aspromonte et al.
Analytical and bioanalytical chemistry, 412(11), 2537-2544 (2020-02-18)
Most of the reported methods for the analysis of volatile methylsiloxanes focus on their environmental fate or possible health effects, aiming at trace level analysis by using direct injection gas chromatography. However, system contamination as carry over and side reactions
Tri Manh Tran et al.
Chemosphere, 184, 1117-1124 (2017-07-05)
Earlier studies have reported the occurrence of cyclic and linear siloxanes in personal care and household products. Nevertheless, there is a lack of information on the occurrence of siloxanes in indoor air. In this study, four cyclic and six linear
De-Gao Wang et al.
The Science of the total environment, 574, 1254-1260 (2016-09-25)
We measured the concentrations of linear and cyclic volatile methylsiloxanes (VMS) concentrations in the blood plasma of turtles, cormorants, and seals collected from Canadian freshwater and marine ecosystems. A modified quick, easy, cheap, effective, rugged, and safe (QuEChERS) method was
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