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Merck

PRKCD

protein kinase C, delta

Synonyms:
MAY1, PKCD, nPKC-delta
Species:
UniProtKB ID:
Gene ID:
  • Human(5580) Summary: Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play distinct roles in cells. The protein encoded by this gene is one of the PKC family members. Studies both in human and mice demonstrate that this kinase is involved in B cell signaling and in the regulation of growth, apoptosis, and differentiation of a variety of cell types. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq, Jul 2008]
  • Mouse(18753) protein kinase C, delta
  • Rat(170538) protein kinase C, delta
  • domestic cat(101087716) protein kinase C, delta
  • chicken(415905) protein kinase C, delta
  • domestic guinea pig(100726624) protein kinase C, delta
  • naked mole-rat(101718422) protein kinase C, delta
  • sheep(101107639) protein kinase C, delta
  • Domestic Rabbit(100008966) protein kinase C, delta
  • cow(505708) protein kinase C, delta
  • sheep(100294651) protein kinase C, delta
  • dog(494005) protein kinase C, delta

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Small Molecule - Agonist

Product Number
Description
Species
Oleic acid, ≥99% (GC),
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-PKC δ antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunohistochemistry

western blot
Anti-phospho-PKC δ (pTyr52) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunofluorescence

immunohistochemistry

western blot
Anti-Protein Kinase Cδ antibody produced in rabbit, whole antiserum,
Species Reactivity
rat
Application
dot blot
microarray

western blot
Anti-phospho-PKCδ (Ser664) Antibody, Upstate®, from rabbit,
Species Reactivity
human
Application
western blot
Anti-PRKCD antibody produced in rabbit, Ab1, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry

western blot

Small Molecule - Inhibitor

Product Number
Description
Species
Phorbol 12,13-dibutyrate, ≥98% (TLC), powder,
Species
mouse
H-7 dihydrochloride, ≥98% (HPLC),
Species
human
Tamoxifen citrate salt, ≥99%,
Species
human
Oleic acid, ≥99% (GC),
Species
human
UCN-01, ≥97% (HPLC), powder,
Species
human

Proteins

Product Number
Description
Species
PKC-δ, active, GST tagged human, PRECISIO®, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human
PKCδ Protein, active, 10 µg, Active, N-terminal His6-tagged, recombinant amino acids 2-end, of human PKCδ. For use in Kinase Assays.,
Species
human
Protein Kinase Cδ isozyme human, >95% (SDS-PAGE), recombinant, expressed in baculovirus infected insect cells, buffered aqueous glycerol solution,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Prkcd,
Species
mouse
MISSION® esiRNA, targeting human PRKCD,
Species
human