T3577

Tolperisone -hydrochlorid

≥98% (HPLC), solid

• Synonym(e): 2-Methyl-1-(4-methylphenyl)-3-(1-piperidyl)propan-1-one -hydrochlorid
• Empirische Formel (Hill-System): C₁₆H₂₃NO · HCl
• CAS-Nummer: 3644-61-9
• Molekulargewicht: 281.82
• EG-Nummer: 222-876-5
• MDL-Nummer: MFCD00058211
• UNSPSC-Code: 12352200
• PubChem Substanz-ID: 329826771
• NACRES: NA.77

Eigenschaften

• Assay: ≥98% (HPLC)
• Form: solid
• Lagerbedingungen: desiccated
• Farbe: white
• Löslichkeit: H₂O: >20 mg/mL
• Lagertemp.: room temp
• SMILES String: Cl.CC(CN1CCCCC1)C(=O)c2ccc(C)cc2
• InChI: 1S/C16H23NO.ClH/c1-13-6-8-15(9-7-13)16(18)14(2)12-17-10-4-3-5-11-17;/h6-9,14H,3-5,10-12H2,1-2H3;1H
• InChIKey: ZBUVYROEHQQAKL-UHFFFAOYSA-N

Beschreibung

Biochem./physiol. Wirkung

Tolperisone is derived from piperidine and possesses membrane stabilizing action. It helps in reducing the effect of spasticities associated with the nervous and muscular system. It exhibits muscle relaxant action through attenuating voltage-gated sodium channels in the brain stem.

Tolperisone regulates ionic currents in myelinates axons and subsequently decreases excitability and mediates its antispastic functions³.

Tolperisone is an ion channel blocker and centrally acting muscle relaxant.

Angaben zur Herstellung

Tolperisone hydrochloride dissolves in water at a concentration that is greater than 20 mg/ml.

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H302 + H312 + H332
• P-Sätze: P261 - P264 - P280 - P301 + P312 - P302 + P352 + P312 - P304 + P340 + P312
• Gefahreneinstufungen: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: dust mask type N95 (US), Eyeshields, Gloves