IL-38 (IL-1F10) mRNA is expressed in heart, placenta, fetal liver, spleen, thymus and tonsil. The expression in a variety of immune tissues and similarity to IL-1Ra suggest a role of IL-1F10 in the inflammatory response.
Physikalische Form
Lyophilized from PBS and 0.5% trehalose.
Rekonstituierung
Reconstitute with 100 μL deionized water.
Sonstige Hinweise
IL-38 [IL-1F10] (mouse) (aa 3-152) is fused at the C-terminus to a FLAG-tag.
Rechtliche Hinweise
FLAG is a registered trademark of Merck KGaA, Darmstadt, Germany
Knowledge of interleukin-38 (IL-38), formerly IL-1 family member 10, is sparse, but Il1f10 polymorphisms are associated with inflammatory diseases, and recombinant IL-38 inhibits inflammatory responses similar to those reported in the context of systemic lupus erythematosus (SLE). We undertook this
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