SRP4969

Epigen (EPGN) human

recombinant, expressed in E. coli, ≥98% (SDS-PAGE)

• Synonym(e): ALGV3072, EPG, EPGN, Epigen, FLJ75542, PRO9904
• UNSPSC-Code: 12352202
• NACRES: NA.32

Eigenschaften

• Biologische Quelle: human
• Rekombinant: expressed in E. coli
• Assay: ≥98% (SDS-PAGE)
• Form: lyophilized
• Wirksamkeit: 150-300 ng/mL
• Mol-Gew.: ~7.9 kDa
• Verpackung: pkg of 25 μg
• Verunreinigungen: endotoxin, tested
• NCBI-Hinterlegungsnummer: Q6UW88
• UniProt-Hinterlegungsnummer: Q6UW88
• Versandbedingung: wet ice
• Lagertemp.: −20°C
• Angaben zum Gen: human ... EPGN(255324)

Beschreibung

Allgemeine Beschreibung

The precursor EPGN (epigen) is a transmembrane glycoprotein and is widely expressed in human tissues. The precursor is cleaved to give a soluble EGF (epidermal growth factor)-like domain.
Recombinant Human epigen, produced in Escherichia coli is a single, non-glycosylated, polypeptide chain containing 72 amino acids and having a molecular mass of 7.9kDa.

Biochem./physiol. Wirkung

EPGN (epigen) is a ligand for EGFR (epidermal growth factor receptor). EPGN (epigen) belongs to the EGF family and enhances proliferation in keratinocytes.

Physikalische Form

EPGN was lyophilized from 20 mM PBS buffer pH-7.4 containing 130 mM sodium chloride.

Rekonstituierung

Centrifuge the vial prior to opening. Avoid freeze-thaw cycles.

Reconstitute in sterile d-H₂O not less than 100 μg/ml. For long term storage, it is recommended to add a carrier protein (0.1% HSA or BSA).