SRP4633

VEGF-C human

recombinant, expressed in E. coli, ≥90% (SDS-PAGE)

• Synonym(e): VEGFC, Vascular Endothelial Growth Factor-C
• MDL-Nummer: MFCD03458368
• UNSPSC-Code: 12352202
• NACRES: NA.32

Eigenschaften

• Biologische Quelle: human
• Rekombinant: expressed in E. coli
• Assay: ≥90% (SDS-PAGE)
• Form: lyophilized
• Mol-Gew.: 15-16 kDa
• Verpackung: pkg of 10 μg
• Lagerbedingungen: avoid repeated freeze/thaw cycles
• Verunreinigungen: endotoxin, tested
• NCBI-Hinterlegungsnummer: Q6FH59
• Versandbedingung: wet ice
• Lagertemp.: −20°C
• Angaben zum Gen: human ... VEGFC(7424)

Beschreibung

Allgemeine Beschreibung

The recombinant VEGF-C (vascular endothelial growth factor-C) is a 125 amino acid protein that lacks the N-terminal signal peptide (from T103 to R227 of Gene Bank U58111). Human VEGF-C exhibits about 85% homology with mouse VEGF-C. The VEGFC gene is mapped to human chromosome 4q34.3.

Anwendung

VEGF-C human has been used to determine cell proliferation and survival.

Biochem./physiol. Wirkung

VEGF-C (vascular endothelial growth factor-C) promotes tumorigenesis, by inducing lymphatic metastasis. The production of VEGF-C is stimulated by pro-fibrotic transforming growth factor β. The main function of VEGF-C is to mediate lymphangiogenesis. Overexpression of VEGF-C in keratinocytes of skin causes dermal lymphatic vessel hyperplasia.

Physikalische Form

Lyophilized without additives.

Rekonstituierung

Centrifuge the vial prior to opening. Avoid freeze-thaw cycles.

Reconstitute in 0.1% acetic acid to a concentration of 0.1-1.0 mg/mL.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable