SRP0697

TAU-316 Protein

recombinant

• UNSPSC-Code: 12352202
• NACRES: NA.77

Eigenschaften

• Rekombinant: expressed in E. coli
• Assay: 70-95% (SDS-PAGE)
• Form: frozen liquid
• Mol-Gew.: ~39 kDa
• Konzentration: 0.2 μg/μL
• Hinterlegungsnummer: P10636-3
• Versandbedingung: dry ice
• Lagertemp.: −70°C
• Angaben zum Gen: human ... MAPT(4137)

Beschreibung

Anwendung

Useful for kinase assay and Western blot.

Biochem./physiol. Wirkung

Recombinant full-length human tag-free Tau-316 was expressed in E. coli cells. Tau-316 encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. Tau-316 transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type ⁽¹⁾. Tau-316 gene mutations have been associated with several neurodegenerative disorders such as Alzheimer′s disease, Pick′s disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy ⁽²⁾.

Sequenz

Full Length

Rekonstituierung

Formulated in 50mM Tris-HCl, pH 7.5, 150 mM NaCl, 0.25 mM DTT, 0.1 mM PMSF, with 25% glycerol.

Lagerung und Haltbarkeit

Store in aliquots at -70°C. Avoid freeze/thaw cycles.

Sicherheitshinweise

• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: WGK 1
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable