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SML2503

Sigma-Aldrich

Pellitorin

≥97% (HPLC)

Synonym(e):

(2E,4E)-N-Isobutyl-2,4-decadienamid, 2E,4E-Decadiensäure-N-Isobutylami

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About This Item

Empirische Formel (Hill-System):
C14H25NO
CAS-Nummer:
18836-52-7
Molekulargewicht:
223.35
MDL-Nummer:
MFCD01735995
UNSPSC-Code:
51111800
NACRES:
NA.77

Assay

≥97% (HPLC)

Form

powder

Lagerbedingungen

desiccated

Farbe

white to beige

Löslichkeit

DMSO: 2 mg/mL, clear

Lagertemp.

−20°C

InChI

1S/C14H25NO/c1-4-5-6-7-8-9-10-11-14(16)15-12-13(2)3/h8-11,13H,4-7,12H2,1-3H3,(H,15,16)/b9-8+,11-10+

InChIKey

MAGQQZHFHJDIRE-BNFZFUHLSA-N

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Biochem./physiol. Wirkung

Pellitorine is an α-Glucosidase inhibitor isolated from the roots of Piper Nigrum that exhibit anti-diabetic, anti-cancer, anti-bacterial and anti-inflammatory properties. Pellitorine is an ACAT (Acyl-CoA cholesteryl acyl transferase) inhibitor that inhibits cholesterol esterification in HepG2 cells. Also pellitorine exhibit potent larvicide activity in mosquito by Inhibition of gene expression encoding V-type H+-ATPase and aquaporine 4. Some new research suggests that anti-adipogenic activity of pellitorine depends on TRPV1.

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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Haribalan Perumalsamy et al.
PloS one, 8(11), e80226-e80226 (2013-11-22)
The yellow fever mosquito, Aedes aegypti, is a vector for transmitting dengue fever and yellow fever. In this study, we assessed the histopathological and molecular effects of pellitorine, an isobutylamide alkaloid, on the third instar of Ae. aegypti larvae. At
Barbara Lieder et al.
Frontiers in pharmacology, 8, 316-316 (2017-06-18)
Adipose tissue is an important endocrine organ in the human body. However, pathological overgrowth is associated with chronic illness. Regulation of adipogenesis and maturation of adipocytes via bioactive compounds in our daily diet has been in focus of research in
Gwendoline Cheng Lian Ee et al.
Molecules (Basel, Switzerland), 15(4), 2398-2404 (2010-04-30)
Pellitorine (1), which was isolated from the roots of Piper nigrum, showed strong cytotoxic activities against HL60 and MCT-7 cell lines. Microbial transformation of piperine (2) gave a new compound 5-[3,4-(methylenedioxy)phenyl]-pent-2-ene piperidine (3). Two other alkaloids were also found from

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