The recommended storage temperature for item P49007 is room temperature. This product is not assigned an expiration date or recommended retest date. Products with no expiration date or recommended retest date should be routinely inspected by customers to ensure they perform as expected. These products are also subject to a one-year warranty from the date of shipment. For more information, you may access the "Product Dating Information" document under "ADDITIONAL USEFUL DOCUMENTS ABOUT OUR PRODUCTS" at the bottom of the Quality Services page with this link: https://www.sigmaaldrich.com/life-science/quality-and-regulatory-management/quality-services.
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P49007
Piperin
≥97%
Synonym(e):
1-Piperoyl-piperidin
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1 G
24,80 €
5 G
30,00 €
About This Item
Empirische Formel (Hill-System):
C17H19NO3
CAS-Nummer:
Molekulargewicht:
285.34
Beilstein:
90741
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
12352100
PubChem Substanz-ID:
NACRES:
NA.22
Empfohlene Produkte
Qualitätsniveau
Assay
≥97%
Form
crystalline
powder, crystals or chunks
solid
mp (Schmelzpunkt)
131-135 °C (lit.)
SMILES String
O=C(\C=C\C=C\c1ccc2OCOc2c1)N3CCCCC3
InChI
1S/C17H19NO3/c19-17(18-10-4-1-5-11-18)7-3-2-6-14-8-9-15-16(12-14)21-13-20-15/h2-3,6-9,12H,1,4-5,10-11,13H2/b6-2+,7-3+
InChIKey
MXXWOMGUGJBKIW-YPCIICBESA-N
Angaben zum Gen
human ... CYP3A4(1576)
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Anwendung
Reactant for synthesis of:
- Dimeric amide alkaloids[1]
- Piperoyl-amino acid conjugates used for antileishmanial activity[2]
- Piperine derived amides with TRPV1 activity[3]
- Piperine analogues as S. aureus NorA efflux pump inhibitors[4]
- Bioactive conjugates of curcumin with antimicrobial and antiproliferative properties[5]
- Piperine derivatives for use as trypanocidal agents[6]
Signalwort
Warning
H-Sätze
Gefahreneinstufungen
Acute Tox. 4 Oral - Aquatic Chronic 2
Lagerklassenschlüssel
11 - Combustible Solids
WGK
WGK 2
Flammpunkt (°F)
Not applicable
Flammpunkt (°C)
Not applicable
Persönliche Schutzausrüstung
dust mask type N95 (US), Eyeshields, Gloves
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V. R. S. Rao, et al.,
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Molecular diversity, 25(1), 233-248 (2020-03-05)
Piperine is the main active component of Piper longum L., which is also the main component of anti-sciatica Mongolian medicine Naru Sanwei pill. It has many pharmacological activities such as anti-inflammatory and immune regulation. This paper aims to preliminarily explore
Welisson da Silva Ferreira et al.
Bioorganic & medicinal chemistry, 16(6), 2984-2991 (2008-01-30)
We herein describe the synthesis and characterization of nine new 1,3,4-thiadiazolium-2-phenylamine chlorides derived from natural piperine. We evaluate their toxic effects against the different evolutive forms of Trypanosoma cruzi, and the host cell (murine macrophages). The results obtained show that
Janine Zaugg et al.
Journal of natural products, 73(2), 185-191 (2010-01-21)
A plant extract library was screened for GABA(A) receptor activity making use of a two-microelectrode voltage clamp assay on Xenopus laevis oocytes. An ethyl acetate extract of black pepper fruits [Piper nigrum L. (Piperaceae) 100 microg/mL] potentiated GABA-induced chloride currents
Shiv K Dubey et al.
European journal of medicinal chemistry, 43(9), 1837-1846 (2008-01-19)
The monoesters of curcumin, a symmetric diphenol with valine and glycine have been prepared by a novel solid phase synthesis and its diesters with valine, glutamic acid and demethylenated piperic acid have been prepared by solution phase method. The assessment
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piperine (5g) is currently on sale. When does it expire? How long can it be stored?
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