SML1616

ICA-069673

≥98% (HPLC)

• Synonym(e): ICA 069673, N-(2-Chloro-5-pyrimidinyl)-3,4-difluoro-benzamide
• Empirische Formel (Hill-System): C₁₁H₆ClF₂N₃O
• CAS-Nummer: 582323-16-8
• Molekulargewicht: 269.63
• MDL-Nummer: MFCD20926351
• UNSPSC-Code: 12352200
• PubChem Substanz-ID: 329825502
• NACRES: NA.77

Eigenschaften

• Qualitätsniveau: 100
• Assay: ≥98% (HPLC)
• Form: powder
• Farbe: white to beige
• Löslichkeit: DMSO: 20 mg/mL, clear
• Lagertemp.: room temp
• SMILES String: O=C(C1=CC=C(F)C(F)=C1)NC2=CN=C(Cl)N=C2
• InChI: 1S/C11H6ClF2N3O/c12-11-15-4-7(5-16-11)17-10(18)6-1-2-8(13)9(14)3-6/h1-5H,(H,17,18)
• InChIKey: IIBSHMFXVWTQSJ-UHFFFAOYSA-N

Beschreibung

Biochem./physiol. Wirkung

ICA-069673 has higher selectivity towards KV7.2/KV7.3 heterodimeric channels than KV7.3/KV7.5 channels. ICA-069673 is considered as a part of gating modifiers.[1]

ICA-069673 is an orally active, potent and selective KV7.2/KV7.3 (KCNQ2/Q3) channel opener that is active in rodent epilepsy models.

ICA-069673 is an orally active, potent and selective KV7.2/KV7.3 (KCNQ2/Q3) channel opener.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3