SML1263

Arylquin 1

≥98% (HPLC)

• Synonym(e): 3-(2-Fluorophenyl)-N7,N7-dimethylquinoline-2,7-diamine)
• Empirische Formel (Hill-System): C₁₇H₁₆FN₃
• CAS-Nummer: 1630743-73-5
• Molekulargewicht: 281.33
• MDL-Nummer: MFCD28580129
• UNSPSC-Code: 12352200
• PubChem Substanz-ID: 329825755
• NACRES: NA.77

Eigenschaften

• Assay: ≥98% (HPLC)
• Form: powder
• Farbe: , white to yellow to light brown
• Löslichkeit: DMSO: 20 mg/mL, clear
• Lagertemp.: 2-8°C
• SMILES String: NC1=NC2=CC(N(C)C)=CC=C2C=C1C3=CC=CC=C3F
• InChI: 1S/C17H16FN3/c1-21(2)12-8-7-11-9-14(17(19)20-16(11)10-12)13-5-3-4-6-15(13)18/h3-10H,1-2H3,(H2,19,20)
• InChIKey: RHAQINSYYSNKKI-UHFFFAOYSA-N

Beschreibung

Biochem./physiol. Wirkung

Arylquin 1 is a potent secretagogue of the tumor suppressor protein prostate apoptosis response-4 (Par-4), selectively inducing apoptosis in a variety of cancer cells. Arylquin 1 acts by binding to vimentin, displacing Par-4 from vimentin for secretion. Arylquin 1 produced a dose-dependent secretion of Par-4 at nanomolar concentrations.

Arylquin 1 is a potent secretagogue of the tumor suppressor protein prostate apoptosis response-4 (Par-4).

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable