SML0818

A-841720

≥98% (HPLC)

• Synonym(e): 9-(Dimethylamino)-3-(hexahydro-1H-azepin-1-yl)-pyrido[3′,2′:4,5]thieno[3,2-d]pyrimidin-4(3H)-one
• Empirische Formel (Hill-System): C₁₇H₂₁N₅OS
• CAS-Nummer: 869802-58-4
• Molekulargewicht: 343.45
• UNSPSC-Code: 12352202
• NACRES: NA.77

Eigenschaften

• Assay: ≥98% (HPLC)
• Form: powder
• Farbe: white to beige
• Löslichkeit: DMSO: 15 mg/mL, clear
• Lagertemp.: 2-8°C
• SMILES String: [s]1c2nccc(c2c3nc[n]([c](c31)=O)N4CCCCCC4)N(C)C
• InChI: 1S/C17H21N5OS/c1-20(2)12-7-8-18-16-13(12)14-15(24-16)17(23)22(11-19-14)21-9-5-3-4-6-10-21/h7-8,11H,3-6,9-10H2,1-2H3
• InChIKey: GYWGXEGOXODOQU-UHFFFAOYSA-N

Beschreibung

Biochem./physiol. Wirkung

A-841720 is a potent, selective, non-competitive mGluR1 antagonist that displays greater than 30-fold selectivity over another Group I metabotopic glutamate receptor, mGluR5. The compound has potent analgesic properties, and can also diminish motor and cognitive activity.

A-841720 is a potent, selective, non-competitive mGluR1 antagonist.

Leistungsmerkmale und Vorteile

This compound is featured on the Glutamate Receptors (G Protein Family) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable