SML0452

AZ513

≥98% (HPLC)

• Synonym(e): 2,3-Dichloro-N-(1H-pyrrolo[2,3-b]pyridin-5-yl)benzamide
• Empirische Formel (Hill-System): C₁₄H₉Cl₂N₃O
• CAS-Nummer: 1335231-15-6
• Molekulargewicht: 306.15
• MDL-Nummer: MFCD22666398
• UNSPSC-Code: 12352200
• PubChem Substanz-ID: 329824731
• NACRES: NA.77

Eigenschaften

• Assay: ≥98% (HPLC)
• Form: powder
• Farbe: white to beige
• Löslichkeit: DMSO: 15 mg/mL (clear solution)
• Lagertemp.: 2-8°C
• SMILES String: Clc1cccc(C(=O)Nc2cnc3[nH]ccc3c2)c1Cl
• InChI: 1S/C14H9Cl2N3O/c15-11-3-1-2-10(12(11)16)14(20)19-9-6-8-4-5-17-13(8)18-7-9/h1-7H,(H,17,18)(H,19,20)
• InChIKey: SIMLBFHHXAMGGM-UHFFFAOYSA-N

Beschreibung

Biochem./physiol. Wirkung

AZ513 is a reversible, noncompetitive FAAH inhibitor.

AZ513 is a reversible, noncompetitive FAAH inhibitor. It also binds non-competitively at a site distinct from the catalytic site. AZ513 is 20-fold more potent against rat FAAH (IC₅₀ 27 nM) than the human form (IC₅₀ 551 nM).

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H302
• Gefahreneinstufungen: Acute Tox. 4 Oral
• Lagerklassenschlüssel: 13 - Non Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable