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Merck

SMB00114

Sigma-Aldrich

Rhodomyrtone

≥95% (LC/MS-ELSD)

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About This Item

Empirische Formel (Hill-System):
C26H34O6
CAS-Nummer:
Molekulargewicht:
442.54
UNSPSC-Code:
12352205
PubChem Substanz-ID:
NACRES:
NA.25

Assay

≥95% (LC/MS-ELSD)

Form

solid

Anwendung(en)

metabolomics
vitamins, nutraceuticals, and natural products

Lagertemp.

−20°C

SMILES String

CC(C)CC1c2c(O)c(C(=O)CC(C)C)c(O)cc2OC3=C1C(=O)C(C)(C)C(=O)C3(C)C

InChI

1S/C26H34O6/c1-12(2)9-14-18-17(11-16(28)20(21(18)29)15(27)10-13(3)4)32-23-19(14)22(30)25(5,6)24(31)26(23,7)8/h11-14,28-29H,9-10H2,1-8H3

InChIKey

TYDBFNAOFZIICW-UHFFFAOYSA-N

Allgemeine Beschreibung

Natural product derived from plant source.
Rhodomyrtone is an acylphloroglucinol compound present in Rhodomyrtus tomentosa.

Anwendung

Rhodomyrtone has been used as a positive control for the identification of rhodomyrtone in Rhodomyrtus tomentosa crude extract by thin-layer chromatography.

Biochem./physiol. Wirkung

Rhodomyrtone belongs to a novel compound class, shows anti-bacterial action against many Gram-positive bacteria (Enterococcus, Bacillus, Staphylococcus, and Streptococcus species) and other pathogenic bacteria. It is known to have greater selectivity for bacterial over mammalian membrane lipids. Rhodomyrtone acts on several cellular processes.

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


Analysenzertifikate (COA)

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Die Dokumentenbibliothek aufrufen

Surasak Limsuwan et al.
Phytomedicine : international journal of phytotherapy and phytopharmacology, 16(6-7), 645-651 (2009-03-24)
Rhodomyrtone [6,8-dihydroxy-2,2,4,4-tetramethyl-7-(3-methyl-1-oxobutyl)-9-(2-methylpropyl)-4,9-dihydro-1H-xanthene-1,3(2H)-di-one] from Rhodomyrtus tomentosa (Aiton) Hassk. displayed significant antibacterial activities against gram-positive bacteria including Bacillus cereus, Bacillus subtilis, Enterococcus faecalis, Staphylococcus aureus, methicillin-resistant S. aureus (MRSA), Staphylococcus epidermidis, Streptococcus gordonii, Streptococcus mutans, Streptococcus pneumoniae, Streptococcus pyogenes, and Streptococcus salivarius.
Suttiwan Wunnoo et al.
Antibiotics (Basel, Switzerland), 10(2) (2021-01-28)
Rhodomyrtone, a plant-derived principal compound isolated from Rhodomyrtus tomentosa (Myrtaceae) leaf extract, was assessed as a potential natural alternative for the treatment of acne vulgaris. The clinical efficacy of a 1% liposomal encapsulated rhodomyrtone serum was compared with a marketed
Antibacterial and Antioxidant Activity of Rhodomyrtus Tomentosa and Cinnamomum Zeylanicum Crude Extracts
Lan TTQ, et al.
Veterinary Science Research, 3(1) (2021)
Dennapa Saeloh et al.
PLoS pathogens, 14(2), e1006876-e1006876 (2018-02-17)
The acylphloroglucinol rhodomyrtone is a promising new antibiotic isolated from the rose myrtle Rhodomyrtus tomentosa, a plant used in Asian traditional medicine. While many studies have demonstrated its antibacterial potential in a variety of clinical applications, very little is known

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