The details of the manufacturing processing cannot be shared, for proprietary reasons, but the product is not sterile filtered. It is is packaged under aseptic conditions.
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SBR00068
Streptomycin Ready Made Solution
100 mg/mL in water
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About This Item
Preise und Verfügbarkeit sind derzeit nicht verfügbar.
Empfohlene Produkte
Form
liquid
Qualitätsniveau
Spezifische Aktivität
(Antibacterial)
Konzentration
100 mg/mL in water
Wirkungsspektrum von Antibiotika
Gram-negative bacteria
Gram-positive bacteria
mycobacteria
Wirkungsweise
protein synthesis | interferes
Lagertemp.
−20°C
SMILES String
[S](=O)(=O)(O)O.[S](=O)(=O)(O)O.[S](=O)(=O)(O)O.N([C@@H]4[C@@H](O[C@H]([C@@H]([C@H]4O)O)CO)O[C@H]5[C@@H](O[C@H]([C@]5(O)C=O)C)O[C@H]6[C@@H]([C@H]([C@@H]([C@H]([C@@H]6O)O)N=C(N)N)O)N=C(N)N)C.N([C@@H]1[C@@H](O[C@H]([C@@H]([C@H]1O)O)CO)O[C@H]2[C@@H](O[C@H]([
InChI
1S/2C21H39N7O12.3H2O4S/c2*1-5-21(36,4-30)16(40-17-9(26-2)13(34)10(31)6(3-29)38-17)18(37-5)39-15-8(28-20(24)25)11(32)7(27-19(22)23)12(33)14(15)35;3*1-5(2,3)4/h2*4-18,26,29,31-36H,3H2,1-2H3,(H4,22,23,27)(H4,24,25,28);3*(H2,1,2,3,4)/t2*5-,6-,7-,8+,9-,10-,11-
InChIKey
QTENRWWVYAAPBI-YZTFXSNBSA-N
Allgemeine Beschreibung
Chemical structure: aminoglycoside
Anwendung
Streptomycin is used to study mechanisms of streptomycin resistance and is often used together with penicillin and other agents to inhibit bacterial contamination in cell culture applications. It is recommended for use in molecular biology applications at 25-50 μg/mL, in cell culture applications at 100 mg/L and in embryo culture at 50 mg/L.
Biochem./physiol. Wirkung
Mode of Action: Streptomycin acts by inhibiting prokaryote protein synthesis by binding to the S12 protein of the 30S ribosomal subunit, thus preventing the transition from imitation complex to chain-elongating ribosome. This causes miscoding or inhibits initiation.
Mode of Resistance: A mutation in rpsL, a gene for S12 ribosomal protein, prevents binding of streptomycin to the ribosome. An aminoglycoside phosphotransferase also inactivates streptomycin.
Antimicrobial spectrum: Streptomycin acts against gram-negative and gram-positive bacteria.
Mode of Resistance: A mutation in rpsL, a gene for S12 ribosomal protein, prevents binding of streptomycin to the ribosome. An aminoglycoside phosphotransferase also inactivates streptomycin.
Antimicrobial spectrum: Streptomycin acts against gram-negative and gram-positive bacteria.
Lagerung und Haltbarkeit
- Streptomycin ready made solution contains 100 mg/mL streptomycin sulfate in water.
- Streptomycin: sulfate salt ratio is 1:1.5.
- The product is packed under aseptic conditions.
Signalwort
Warning
H-Sätze
Gefahreneinstufungen
Repr. 2
Lagerklassenschlüssel
10 - Combustible liquids
WGK
WGK 3
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Streptomycin ready made solution 100mg/ml cat # SBR00068 : is the solution filtered at the end of the preparation? Thank you
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