The specific epitope sequence is not available. This gene is mapped to human chromosome 11q23.2–11q23.3. The immunogen is a phospho-peptide corresponding to Phospho-Histone H2AX (Ser139).
SAB5600038
Anti-Gamma H2AX (phospho-Ser139) antibody, Rabbit monoclonal
recombinant, expressed in HEK 293 cells, clone RM224, purified immunoglobulin
Synonym(e):
H2AX Ser139 p, Histone H2AX (phospho ser139)
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100 μG
501,00 €
501,00 €
Versandbereit am28. April 2025Details
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100 μG
501,00 €
About This Item
UNSPSC-Code:
12352203
NACRES:
NA.41
501,00 €
Versandbereit am28. April 2025Details
Empfohlene Produkte
Rekombinant
expressed in HEK 293 cells
Qualitätsniveau
Antikörperform
purified immunoglobulin
Antikörper-Produkttyp
primary antibodies
Klon
RM224, monoclonal
recombinant monoclonal
Form
buffered aqueous glycerol solution
Speziesreaktivität
human
Konzentration
~1 mg/mL
Methode(n)
ELISA: 0.2- 1 μg/mL
immunoblotting: 0.5-2 μg/mL
immunocytochemistry: 0.5-2 μg/mL
Isotyp
IgG
NCBI-Hinterlegungsnummer
Versandbedingung
wet ice
Lagertemp.
−20°C
Posttranslationale Modifikation Target
phosphorylation (pSer139)
Angaben zum Gen
human ... H2AX(3014)
Allgemeine Beschreibung
Histone H2AX (H2A histone family member X), a histone variant present in almost all eukaryotes, is coded by H2AFX gene. It is mapped to human chromosome 11q23.2–11q23.3.
Spezifität
This antibody reacts to Histone H2A.X only when phosphorylated at serine 139. No cross reactivity with other phosphorylated histones.
Immunogen
Synthetic peptide corresponding to Phospho-Histone H2AX (Ser139)
Biochem./physiol. Wirkung
H2AX (H2A histone family member X) helps to maintain genome stability. It plays an important role in localisation and structuring of the repair focus. H2AX also plays an active role in supplying the active repair proteins. γH2AX participates in DSB repair. This protein serves as a signal and target of phosphorylation in the spreading phase.
Leistungsmerkmale und Vorteile
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Physikalische Form
Solution in phosphate buffered saline containing 50% glycerol, 1% BSA and 0.09% sodium azide.
Haftungsausschluss
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Lagerklassenschlüssel
10 - Combustible liquids
WGK
WGK 2
Flammpunkt (°F)
Not applicable
Flammpunkt (°C)
Not applicable
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I pretend to use this antibody with another organism, so I need to know the inmunogenic sequence or epitope.
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