SAB4504605

Anti-phospho-AXL (pTyr⁶⁹⁸) antibody produced in rabbit

affinity isolated antibody

• Synonym(e): Anti-ARK, Anti-JTK11, Anti-Tyro7, Anti-UFO
• UNSPSC-Code: 12352203
• NACRES: NA.41

Eigenschaften

• Biologische Quelle: rabbit
• Qualitätsniveau: 100
• Konjugat: unconjugated
• Antikörperform: affinity isolated antibody
• Antikörper-Produkttyp: primary antibodies
• Klon: polyclonal
• Form: buffered aqueous solution
• Mol-Gew.: antigen 97 kDa
• Speziesreaktivität: human, mouse, rat
• Konzentration: ~1 mg/mL
• Methode(n): ELISA: 1:20000; immunohistochemistry: 1:50-1:100; western blot: 1:500-1:1000
• NCBI-Hinterlegungsnummer: P30530
• UniProt-Hinterlegungsnummer: P30530
• Versandbedingung: wet ice
• Lagertemp.: −20°C
• Posttranslationale Modifikation Target: phosphorylation (pTyr698)
• Angaben zum Gen: human ... AXL(558)

Beschreibung

Allgemeine Beschreibung

AXL (receptor tyrosine kinase) is also termed as Ark, UFO or Tyro7. This gene is overexpressed in pancreatic cancer tissues. AXL belongs to the receptor tyrosine kinase family. It is obtained as a transforming gene from human leukemia cells. AXL is mapped to human chromosome 19q13.

Immunogen

The antiserum was produced against synthesized peptide derived from human AXL around the phosphorylation site of Tyr691.

Immunogen Range: 657-706

Biochem./physiol. Wirkung

AXL (receptor tyrosine kinase) controls innate immune responses. It participates in cellular transformation and tumor progression. Overexpression of AXL is characterized with higher liability for lymphatic metastases.

Leistungsmerkmale und Vorteile

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Physikalische Form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: WGK 1
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable