SAB4501401

Anti-HMGB1 antibody produced in rabbit

affinity isolated antibody

• Synonym(e): HMG-1, HMG1, High mobility group protein 1, High mobility group protein B1
• MDL-Nummer: MFCD02263062
• UNSPSC-Code: 12352203
• NACRES: NA.41

Eigenschaften

• Biologische Quelle: rabbit
• Qualitätsniveau: 100
• Konjugat: unconjugated
• Antikörperform: affinity isolated antibody
• Antikörper-Produkttyp: primary antibodies
• Klon: polyclonal
• Form: buffered aqueous solution
• Mol-Gew.: antigen 24 kDa
• Speziesreaktivität: rat, human, mouse
• Konzentration: ~1 mg/mL
• Methode(n): ELISA: 1:20000; western blot: 1:500-1:1000
• NCBI-Hinterlegungsnummer: P09429
• UniProt-Hinterlegungsnummer: P09429
• Versandbedingung: wet ice
• Lagertemp.: −20°C
• Posttranslationale Modifikation Target: unmodified
• Angaben zum Gen: human ... HMGB1(3146)

Beschreibung

Allgemeine Beschreibung

Anti-HMGB1 Antibody detects endogenous levels of total HMGB1 protein.

High mobility group box 1 (HMGB1) is a nuclear protein that belongs to the damage-associated molecular pattern (DAMP) family. It is located on human chromosome 13q12.

Immunogen

The antiserum was produced against synthesized peptide derived from human HMGB1.

Immunogen Range: 131-180

Biochem./physiol. Wirkung

High mobility group box 1 (HMGB1) is involved in bone remodeling and ectopic calcification pathogenesis. It initiates neuroinflammation after epileptogenic injuries. HMGB1 also binds to chromatin and modulates gene transcription.

Leistungsmerkmale und Vorteile

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Physikalische Form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: nwg
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable