SAB4300685

Anti-ASH2L antibody produced in rabbit

affinity isolated antibody

• Synonym(e): Anti-ASH2, Anti-ASH2L1, Anti-ASH2L2, Anti-Bre2
• UNSPSC-Code: 12352203
• NACRES: NA.41

Eigenschaften

• Biologische Quelle: rabbit
• Qualitätsniveau: 100
• Konjugat: unconjugated
• Antikörperform: affinity isolated antibody
• Antikörper-Produkttyp: primary antibodies
• Klon: polyclonal
• Form: buffered aqueous solution
• Mol-Gew.: 65-80 kDa
• Speziesreaktivität: human
• Konzentration: 1 mg/mL
• Methode(n): western blot: 1:500-1:1000
• Isotyp: IgG
• Immunogene Sequenz: (G-R-R-S-P)
• NCBI-Hinterlegungsnummer: NM_004674.3
• UniProt-Hinterlegungsnummer: Q9UBL3
• Versandbedingung: wet ice
• Lagertemp.: −20°C
• Posttranslationale Modifikation Target: unmodified
• Angaben zum Gen: human ... ASH2L(9070)

Beschreibung

Allgemeine Beschreibung

The antibody detects endogenous level of total ASH2L protein.

Immunogen

Peptide sequence around aa. 620-624 (G-R-R-S-P), according to the protein NP_004665.2

Leistungsmerkmale und Vorteile

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Zielbeschreibung

Component of the Set1/Ash2 histone methyltransferase (HMT) complex, a complex that specifically methylates ′Lys-4′ of histone H3, but not if the neighboring ′Lys-9′ residue is already methylated. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at ′Lys-4′ of histone H3. May function as a transcriptional regulator. May play a role in hematopoiesis.

Physikalische Form

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

Sicherheitshinweise

• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: WGK 1
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable