SAB4200726

Anti-Myosin (Smooth) antibody, Mouse monoclonal

clone hSM-V, purified from hybridoma cell culture

• Synonym(e): Anti-SM
• UNSPSC-Code: 41116158

Eigenschaften

• Biologische Quelle: mouse
• Antikörperform: purified from hybridoma cell culture
• Antikörper-Produkttyp: primary antibodies
• Klon: hSM-V, monoclonal
• Speziesreaktivität: quail, rabbit, rat, human, sheep, bovine, mouse, porcine, canine
• Konzentration: ~1.0 mg/mL
• Methode(n): immunoblotting: suitable; immunofluorescence: suitable; immunohistochemistry: 10-20 μg/mL using methacarn -fixed paraffin-embedded human tonsil sections; immunoprecipitation (IP): suitable
• Isotyp: IgG1
• Versandbedingung: dry ice
• Lagertemp.: −20°C
• Posttranslationale Modifikation Target: unmodified
• Angaben zum Gen: human ... MYH11(4629)

Beschreibung

Allgemeine Beschreibung

Anti-Myosin (Smooth) antibody, Mouse monoclonal (mouse IgG1 isotype) is derived from the hSM-V hybridoma produced by the fusion of mouse myeloma cells and splenocytes from a mouse immunized with human uterus smooth muscle extract. Myosin together with actin belong to a family of contractile proteins. Myosin contains two heavy chains (~200 kDa each) and four light chains (15-26 kDa). The Myosin molecules which consist of two major regions: tail (rod) and head, aggregate through the tail region into filaments and interact through the head region with actin and with ATP.

Immunogen

human uterus smooth muscle extract

Anwendung

Anti-Myosin (Smooth) antibody, Mouse monoclonal has been used in various immunochemical assays, including immunohistochemistry, immunoblotting, immunofluorescence, immunoprecipitation and fluorescence-activated cell sorting (FACS) / flow cytometry.

Biochem./physiol. Wirkung

Myosin is involved in a variety of cellular processes including secretion, cytoplasmic streaming, locomotion, phagocytosis and cytokinesis. This antibody can be a useful tool in the identification and localization of smooth muscle elements, in the diagnosis and classification of mesenchymal tumors and in myosin expression studies in normal and malignant cell proliferations.

Physikalische Form

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: WGK 1
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable