SAB2501686

Anti-NOX1 antibody produced in goat

affinity isolated antibody, buffered aqueous solution

• Synonym(e): GP91-2, MOX1, NADPH oxidase 1, NOH-1
• UNSPSC-Code: 12352203
• NACRES: NA.41

Eigenschaften

• Biologische Quelle: goat
• Qualitätsniveau: 100
• Konjugat: unconjugated
• Antikörperform: affinity isolated antibody
• Antikörper-Produkttyp: primary antibodies
• Klon: polyclonal
• Form: buffered aqueous solution
• Speziesreaktivität: mouse, human, bovine, canine
• Methode(n): indirect ELISA: suitable; western blot: suitable
• UniProt-Hinterlegungsnummer: Q9Y5S8
• Versandbedingung: wet ice
• Lagertemp.: −20°C
• Posttranslationale Modifikation Target: unmodified
• Angaben zum Gen: human ... NOX1(27035)

Beschreibung

Allgemeine Beschreibung

NADPH oxidase 1 (NOX1) is encoded by the gene mapped to human chromosome Xq22.1. The protein belongs to the family of NADPH oxidases and is co-localized with caveolin in punctate patches on the surface and laterally on the cellular margins. NOX1 is mainly expressed in colon epithelium.

Immunogen

Peptide with sequence C-DKATDIVTGLKQK, from the internal region of the protein sequence according toNP_008983.2; NP_39249.1

Anwendung

Anti-NOX1 antibody produced in goat has been used for Western blotting.

Biochem./physiol. Wirkung

NOX1 catalyzes the production of hydrogen peroxide (H₂O₂). Overexpression of the protein leads to the production of superoxide and H₂O₂ and triggers angiogenic switch, mediating vascularization and rapid expansion of the tumor. Elevated expression of NOX1 has been observed in the brain of Parkinson′s disease (PD) patients.

Leistungsmerkmale und Vorteile

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physikalische Form

Supplied at 0.5 mg/mL in 20mM Tris (pH 7.3) and 150mM NaCl with 0.02% sodium azide and 0.5% bovine serum albumin.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: WGK 2
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable