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RAB0332

Sigma-Aldrich

Human Lipocalin-2 / NGAL ELISA Kit

for serum, plasma, cell culture supernatant and urine

Synonym(e):

Lipocalin-2, NGAL, Neutrophil gelatinase-associated lipocalin 

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1 KIT
640,00 €

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1 KIT
640,00 €

About This Item

UNSPSC-Code:
41116158
NACRES:
NA.32

640,00 €


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Speziesreaktivität

human

Verpackung

kit of 96 wells (12 strips x 8 wells)

Methode(n)

ELISA: suitable
capture ELISA: suitable

Aufnahme

sample type serum
sample type plasma
sample type cell culture supernatant(s)
sample type urine

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 4 pg/mL
standard curve range: 4.1-1000 pg/mL

Nachweisverfahren

colorimetric

Versandbedingung

wet ice

Lagertemp.

−20°C

Angaben zum Gen

human ... LCN2(3934)

Verwandte Kategorien

Allgemeine Beschreibung

Lipocalin-2 (LCN2), a secreted glycoprotein, is an adipokine.[1][2] It is expressed in various cells like respiratory cells, intestinal epithelial cells, endothelial cells, renal tubular cells and cardiomyocytes.[3] The gene LCN2 is located on human chromosome 9q34.[4] The human lipocalin-2 ELISA (enzyme-linked immunosorbent assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of human lipocalin-2 in serum, plasma, cell culture supernatants and urine.

Immunogen

Recombinant Human Lipocalin-2

Anwendung

For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Human Lipocalin-2/NGAL ELISA Kit has been used in the electrochemical immunoassay.[5] It has also been used to determine the neutrophil gelatinase-associated lipocalin (NGAL) levels in the urine.[6]

Biochem./physiol. Wirkung

Lipocalin-2 (LCN2) has been implicated in a variety of processes including cell differentiation, tumorigenesis and apoptosis.[3] Polymorphisms in the expression of LCN2 are associated with many cancers such as breast, colorectal, pancreatic, ovarian, gastric, thyroid, ovarian, bladder and kidney cancers.[1]

Sonstige Hinweise

A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.

Kit-Komponenten auch einzeln erhältlich

Produkt-Nr.
Beschreibung
SDB

  • RABELADEELISA 5X Assay/Sample Diluent Buffer E (Item E2)SDB

  • RABSTOP3ELISA Stop Solution (Item I)SDB

  • RABTMB3ELISA Colorimetric TMB Reagent (HRP Substrate, Item H)SDB

  • RABWASH420X Wash Buffer (Item B)SDB

Piktogramme

Corrosion

Signalwort

Warning

H-Sätze

P-Sätze

Gefahreneinstufungen

Met. Corr. 1

Lagerklassenschlüssel

8A - Combustible corrosive hazardous materials


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In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.

Die Dokumentenbibliothek aufrufen

Ai-Li Sun et al.
Mikrochimica acta, 187(9), 485-485 (2020-08-07)
An innovative signal-transduction tag based on cross-linked urease nanoparticles (CLENP) was designed for the development of a pH meter-based immunoassay of lipocalin-2 (LCN2). The CLENP was synthesized with a typical desolvation method using ethanol as desolvation agent, followed by functionalization with polyaspartic
Julio Cezar Q Machado et al.
Journal of physical activity & health, 15(9), 679-682 (2018-08-03)
Neutrophil gelatinase-associated lipocalin (NGAL) is a glycoprotein released during early phases of a postischemic kidney in response to kidney injury, inflammation, and oxidative stress. It can be detected in urine after 2 hours of an ischemic event. The aim was
Expression of neutrophil gelatinase-associated lipocalin in colorectal neoplastic progression: a marker of malignant potential?
McLean MH
British Journal of Cancer, 108, 2537-2537 (2013)
Network based analyses of gene expression profile of LCN2 overexpression in esophageal squamous cell carcinoma
Wu B, et al.
Scientific Reports, 5403-5403 (2014)
Lipocalin 2, the TNF-like receptor TWEAKR and its ligand TWEAK act downstream of NFAT1 to regulate breast cancer cell invasion.
Gaudineau B, et. al.
Journal of Cell Science, 125, 4475-4475 (2012)

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