Cell signaling hormone that is prominent in the prostate, and belongs to the insulin superfamily
Biochem./physiol. Wirkung
Relaxin 1 may function in regulating blood pressure, controlling heart rate, and releasing oxytocin and vasopressin
Relaxin has been shown to have antifibrotic effects in renal fibroblasts through mechanisms that increase collagenase activity and via TGF-β signaling. [1]
Physikalische Form
Lyophilized powder containing BSA
Rekonstituierung
In Phosphate buffered saline solution containing at least 0.1% serum albumin. The concentration should be ≥10 μg/mL
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 19(3), 544-552 (2004-02-10)
Renal fibroblasts are important effector cells in tubulointerstitial fibrosis, with experimental antifibrotic strategies focusing on the functional down-regulation of these cells. Several experimental models of fibrosis have provided evidence for the effectiveness of the polypeptide hormone relaxin as a potential
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