PZ0377

PF-05236216 hydrochloride

≥98% (HPLC)

• Synonym(e): 4-[3-(4-Fluorophenyl)-1-methyl-1H-pyrazol-4-yl]-6,7-dihydro-6-methyl-5H-pyrrolo[3,4-b]pyridin-5-one hydrochloride, PF-5236216 hydrochloride
• Empirische Formel (Hill-System): C₁₈H₁₅FN₄O · HCl
• CAS-Nummer: 1383376-93-9
• Molekulargewicht: 358.80
• UNSPSC-Code: 51111800
• NACRES: NA.77

Eigenschaften

• Assay: ≥98% (HPLC)
• Form: powder
• Lagerbedingungen: desiccated
• Farbe: white to beige
• Löslichkeit: DMSO: 2 mg/mL, clear
• Lagertemp.: 2-8°C
• SMILES String: CN1C=C(C2=CC=NC(CN3C)=C2C3=O)C(C4=CC=C(F)C=C4)=N1.Cl
• InChI: 1S/C18H15FN4O.ClH/c1-22-10-15-16(18(22)24)13(7-8-20-15)14-9-23(2)21-17(14)11-3-5-12(19)6-4-11;/h3-9H,10H2,1-2H3;1H
• InChIKey: CLDJMFXSCFWXDI-UHFFFAOYSA-N

Beschreibung

Biochem./physiol. Wirkung

PF-05236216 is a brain penetrant, potent and selective inhibitor of casein kinase 1 delta/epsilon (CK1δ/ε) that modulates circadian rhythms in mice.

brain penetrant, potent and selective inhibitor of casein kinase 1 delta/epsilon (CK1δ/ε)

Rechtliche Hinweise

Sold for research purposes under agreement from Pfizer Inc.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable