P5806

Pasteurella multocida toxin

lyophilized powder

• Synonym(e): PMT
• CAS-Nummer: 129876-91-1
• MDL-Nummer: MFCD00131803
• UNSPSC-Code: 12352200
• NACRES: NA.77

Eigenschaften

• Sterilität: sterile-filtered
• Qualitätsniveau: 200
• Form: lyophilized powder
• Verpackung: vial of 50 μg toxin (Also contains 10 mM Tris, 0.1 M NaCl, and 0.1% sucrose, pH 8.3.)
• Lagertemp.: −20°C

Beschreibung

Biochem./physiol. Wirkung

Pasteurella multocida toxin (PMT) is a bacterial protein toxin produced by few P. multocida serotype A and D strains. It acts as an effective mitogen in numerous cell types in vitro. PMT inhibits osteoblast differentiation by activating the Rho/Rho-associated coiled-coil containing protein kinase (Rho/ROCK) pathway. Infections of PMT cause atrophic rhinitis in pigs and by local dermatonecrosis, respiratory disease in cattle and rabbits. PMT is also a pathogenic agent of dermatonecrosis and bacteremia in humans.

Leistungsmerkmale und Vorteile

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Sicherheitshinweise

• Lagerklassenschlüssel: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable