M8759

3-Maleimidobenzoesäure N-hydroxysuccinimid-Ester

• Synonym(e): MBS
• Empirische Formel (Hill-System): C₁₅H₁₀N₂O₆
• CAS-Nummer: 58626-38-3
• Molekulargewicht: 314.25
• Beilstein: 1505254
• EG-Nummer: 261-368-8
• MDL-Nummer: MFCD00005514
• UNSPSC-Code: 47101511
• PubChem Substanz-ID: 24897286

Eigenschaften

• mp (Schmelzpunkt): 175-177 °C (lit.)
• Löslichkeit: ethyl acetate or DMF: ≤20 mg/mL (may require addition of solvent to coupling buffer to at least 5% to maintain solubility)
• Lagertemp.: −20°C
• SMILES String: O=C1CCC(N1OC(C2=CC=CC(N3C(C=CC3=O)=O)=C2)=O)=O
• InChI: 1S/C15H10N2O6/c18-11-4-5-12(19)16(11)10-3-1-2-9(8-10)15(22)23-17-13(20)6-7-14(17)21/h1-5,8H,6-7H2
• InChIKey: LLXVXPPXELIDGQ-UHFFFAOYSA-N

Beschreibung

Anwendung

Heterobifunctional crosslinking reagent reactive toward primary amine and sulfhydryl. Typically, coupled initially to molecules containing primary amines by amide bonds buffered at pH 7.0, followed by coupling to compounds containing sulfhydryl by thioether at same pH. Useful for preparation of enzyme immunoconjugates and hapten carrier molecule conjugates.

Sonstige Hinweise

The aryl maleimide is less stable than alkyl maleimide linkers.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: dust mask type N95 (US), Eyeshields, Gloves