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Merck

L9895

Sigma-Aldrich

Lectin from Pseudomonas aeruginosa

lyophilized powder

Synonym(e):

PA-I

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1 MG
131,00 €
2 MG
446,00 €

131,00 €

Listenpreis262,00 €Sparen Sie 50%

Versandbereit am07. April 2025Details



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Ansicht ändern
1 MG
131,00 €
2 MG
446,00 €

About This Item

MDL-Nummer:
UNSPSC-Code:
12352202
NACRES:
NA.32

131,00 €

Listenpreis262,00 €Sparen Sie 50%

Versandbereit am07. April 2025Details


Form

lyophilized powder

Qualitätsniveau

Wirksamkeit

<15 μg/mL per mL agglutination activity

Lagertemp.

−20°C

Biochem./physiol. Wirkung

PA-I has a major affinity for D-galactose and its derivatives. PA-I agglutinates all types of human and animal erythrocytes and interacts also with unicellular protozoa, algae and bacteria. PA-I induces mitogenic stimulation in cultured human lymphocytes pretreated with neuraminidase.

Verpackung

Package size based on protein content. Vial content based on protein by biuret.

Qualität

Highly purified.

Physikalische Form

Lyophilized powder containing approx. 80% protein (biuret), balance primarily sodium citrate, plus traces of calcium chloride, magnesium chloride and manganese chloride

Angaben zur Herstellung

Purified by affinity chromatography using a modification of Gilboa-Garber.1

Hinweis zur Analyse

Agglutination activity is expressed in μg/ml and is determined from serial dilutions of a 1 mg/ml solution using phosphate buffered saline, pH 7.0. This activity is the lowest concentration to agglutinate a 2% suspension of neuraminidase treated human blood group A erythrocytes after one hr incubation at 25 °C.

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, type N95 (US)


Hier finden Sie alle aktuellen Versionen:

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In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.

Die Dokumentenbibliothek aufrufen

Alessandro Palmioli et al.
Chembiochem : a European journal of chemical biology, 20(23), 2911-2915 (2019-06-20)
Biofilm formation by bacterial pathogens is a hallmark of chronic infections and is associated to increased antibiotic tolerance that makes pathogens difficult to eradicate with conventional antibiotic therapies. Infections caused by Pseudomonas aeruginosa are of great concern, especially for immunocompromised
Akiko Chiba et al.
Molecular cancer research : MCR, 18(1), 130-139 (2019-10-20)
Breast tumors have their own specific microbiota, distinct from normal mammary gland tissue. Patients with breast cancer that present with locally advanced disease often undergo neoadjuvant chemotherapy to reduce tumor size prior to surgery to allow breast conservation or limit

Artikel

Find the right lectin for your research with our lectin selection guide, organized by lectin source/species, carbohydrate specificity, blood group specificity, and more.

Fragen

  1. Which one is this, LecA or LecB?

    Which one is this, LecA or LecB?

    1 Antwort
    1. Based on the production protocol of this product, it is directed towards the purification of PA-I only, with PA-II removal. According to the literature, PA-I is LecA and PA-II is LecB. Therefore, it appears that this product is LecA. For more information, please refer to the following literature: [Literature Link](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1698087/)

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