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H4128

Sigma-Aldrich

4-Androsten-11β,17β-diol-3-on

crystalline

Synonym(e):

11β,17β-Dihydroxyandrost-4-en-3-one, 4-Androstene-11β,17β-diol-3-one

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About This Item

Empirische Formel (Hill-System):
C19H28O3
CAS-Nummer:
1816-85-9
Molekulargewicht:
304.42
MDL-Nummer:
MFCD00010481
UNSPSC-Code:
12352200
PubChem Substanz-ID:
24895621

Form

crystalline

Arzneimittelkontrolle

USDEA Schedule III; Home Office Schedule 4.2; regulated under CDSA - not available from Sigma-Aldrich Canada

Farbe

light yellow

SMILES String

CC12CC(O)C3C(CCC4=CC(=O)CCC34C)C1CCC2O

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Biochem./physiol. Wirkung

Structure-activity relationships of 11-substituted testosterone derivatives as progesterone agonists, and their effect on growth and differentiation of human decidual cells.

Piktogramme

Health hazard
GHS08

Signalwort

Danger

H-Sätze

H351,H360

Gefahreneinstufungen

Carc. 2 - Repr. 1B

Lagerklassenschlüssel

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, type P3 (EN 143) respirator cartridges

Analysenzertifikate (COA)

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R Schulz et al.
General and comparative endocrinology, 80(2), 189-198 (1990-11-01)
Testicular tissue collected at different stages of gonadal development was incubated with a pituitary extract (PE) from mature salmon. Three androgens (11-ketotestosterone, OT; 11 beta-hydroxytestosterone, OHT; and testosterone, T) and 17 alpha,20 beta-dihydroxyprogesterone (17-20 beta P) were quantified by radioimmunoassay
S T Chan et al.
Journal of steroid biochemistry, 25(6), 1013-1021 (1986-12-01)
A new method for the simultaneous determination of androstenedione, testosterone, 11-oxotestosterone and 11 beta-hydroxy-testosterone in teleost plasma has been developed. Steroids extracted from the plasma were first separated by Celite chromatography using ethanediol as the stationary phase and different concentrations
T Leitz et al.
General and comparative endocrinology, 66(1), 145-157 (1987-04-01)
Testicular tissues of the Siamese fighting fish were incubated with [14C]pregnenolone for 10, 20, 30, 50, 80, and 120 min, and with [14C]progesterone, [14C]11 beta-hydroxyandrostenedione, [14C]11 beta-hydroxytestosterone, and [14C]androstenetrione for 120 min. 11-Ketotestosterone was the main metabolite in all 120-min
P N Rao et al.
Steroids, 43(3), 343-350 (1984-03-01)
Starting from 11 beta-hydroxytestosterone, we achieved the synthesis of a strategic precursor, C-9 (11) unsaturated 5 alpha-androstane-3 alpha, 17 beta-diol 17-glucuronide (9a), for the preparation of 9 alpha,11 alpha-tritiated 5 alpha-androstane-3 alpha, 17 beta-diol 17-glucuronide. We optimized the reaction conditions
D E Kime et al.
General and comparative endocrinology, 68(2), 189-196 (1987-11-01)
Testosterone, estradiol, and dehydroepiandrosterone (T, E2, and DHA) were measured by RIA in plasma samples from three groups of sexually immature male and female (male, female) river lampreys: (I) intact, (II) gonadectomized, or (III) with pro- and mesoadenohypophysis removed (hypophysectomized).
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