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GE17-5132-03

Glutathione Sepharose 4 Fast Flow

Cytiva 17-5132-03, pack of 500 mL

Synonym(e):

Glutathione Column, Sepharose 4 Fast Flow

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About This Item

UNSPSC-Code:
41106500
NACRES:
NA.56

ligand

glutathione and 10-carbon linker arm

Verpackung

pack of 500 mL

Hersteller/Markenname

Cytiva 17-5132-03

Matrix

highly cross-linked 4% agarose

Durchschnittlicher Durchmesser

90 μm

cleaning

3-12

working range

3-12

Kapazität

>10 mg/mL binding capacity

Allgemeine Beschreibung

Binding of GST to glutathione is flow-rate dependent and lower flow rates often increase the binding capacity. This is important to consider during sample loading and elution.
Glutathione Sepharose 4 Fast Flow, 500 mL
Glutathione Sepharose 4 Fast Flow is an affinity medium for fast, one-step purification of Glutathione S-Transferase (GST) tagged proteins. Provides good flow properties, excellent for scale-up.

Glutathione Sepharose 4 Fast Flow is used for the purification of GST-tagged proteins from bacterial lysates and other S-tranferases or glutathione-dependent proteins. Mild elution conditions preserve protein antigenicity and function. Sepharose 4 Fast Flow provides good flow properties and is excellent for scaling up.

Leistungsmerkmale und Vorteile

  • Fast, one-step purification of GST-tagged proteins
  • Mild elution conditions preserving protein antigenicity and function
  • For scale-up due to high flow properties
  • Glutathione coupled to Sepharose 4 Fast Flow via a 10-carbon spacer arm

Lagerung und Haltbarkeit

Please be aware this product may be shipped 90 days before the expiration date. For more information on the batch specific expiration date, please contact technical service.
Store at 4 to 30 °C (20% Ethanol)

Hinweis zur Analyse

To view the Certificate of Analysis for this product, please visit www.cytiva.com.

Rechtliche Hinweise

Sepharose is a trademark of Cytiva

Piktogramme

Flame

Signalwort

Warning

H-Sätze

Lagerklassenschlüssel

3 - Flammable liquids


Analysenzertifikate (COA)

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Artikel

This page describes general considerations for purification of GST-tagged proteins using Cytiva products.

GST-tagged protein yield varies based on protein, host cell, and culture conditions, influencing production.

This page shows troubleshooting strategies for cleavage methods using Cytiva products.

This page shows how to cleave and purify GST-tagged proteins bound to Glutathione Sepharose in batch mode from Cytiva. Glutathione Sepharose High Performance, Glutathione Sepharose 4 Fast Flow, and Glutathione Sepharose 4B can all be used for cleavage and purification of GST-tagged proteins in batch.

Protokolle

This page shows how to purify GST-tagged proteins using Glutathione Sepharose from Cytiva.

This page how to remove GST tags by enzymatic cleavage using Cytiva products.

GSTrap™ affinity columns are specially designed 1 ml and 5 ml HiTrap® columns packed with Glutathione Sepharose High Performance, Glutathione Sepharose 4 Fast Flow, or Glutathione Sepharose 4B media.

Affinity chromatography tags like GST fusion proteins facilitate separations in various purification products from Cytiva.

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